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Cat. No. Product Name Information
PC-42968

Q-VD-Oph

pan-Caspase inhibitor

Q-VD-Oph (QVD-OPH) is a potent pan-caspase inhibitor, inhibits human recombinant caspase-7 with IC50 of 48 nM in cell-free assay, also inhibits caspase -1, 3, 8, 9, 10, and 12 with IC50 of 25-400 nM.
PC-62433

Emricasan

Caspase inhibitor

Emricasan (IDN-6556, PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.
PC-62211

WF-210

Procaspases-3 activator

WF-210 is a PAC-1 derivative and potent activator of procaspases-3 with EC50 of 0.95 uM, displays more cytotoxic than PAC‐1 to human cancer cells, but less cytotoxic to normal cells.
PC-62210

Procaspase-3 activator 1541B

Procaspases-3 activator

Procaspase-3 activator 1541B is a specific, small molecule activator of procaspases-3 with EC50 of 1.3 uM.
PC-62209

Procaspase-3 activator 1541

Procaspase-3/6 activator

Procaspase-3 activator 1541 is a small-molecule inducer of cell death that noncovalently self-assembles into chemical fibrils and activates procaspase-3 and 6 in vitro (EC50=2.4 and 2.8 uM).
PC-61354

IDN-7314

pan-Caspase inhibitor

IDN-7314 is a potent, orally active, and irreversible pan-Caspase protease inhibitor with IC50 of <0.08 to 7 nM for inhibition of activated caspase 3, 6 and 8.
PC-70208

NWL-117

Caspase-6 inhibitor

NWL-117 is a potent, ​BBB penetrant Caspase-6 inhibitor with IC50 of 192 nM, also inhibits Caspase-4/8/9/10 with IC50 of 0.1-0.8 uM.
PC-60171

KEA1-97

Thioredoxin-Caspase 3 inhibitor

KEA1-97 (KEA 1-97) is a small molecule that disrupts the interaction of thioredoxin with caspase 3.
PC-24912

MMPSI

Caspase 3/Caspase 7 inhibitor

MMPSI is a potent and selective, non-peptide caspase 3/7 inhibitor with Ki app of 0.06 uM and 0.17 uM respective, exhibits >100-fold selectivity over all other family members except caspase 9 (Ki app=3.1 uM).
PC-24911

Ac-DNLD-CHO

Caspase-3 inhibitor

Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is a potent, selective, reversible Caspase-3 inhibitor with IC50 of 9.89 nM, Ki app of 0.68 nM respectively.
PC-24910

XIAP-CASP7 inhibitor 643943

Caspase 7 inhibitor

XIAP-CASP7 inhibitor 643943 is a specific reversible XIAP-caspase 7 (CASP7) PPI inhibitor, binds to CASP7 Cys246 in an allosteric site, causes dissociation of XIAP to activate CASP7 and induces CASP7-mediated apoptosis.
PC-24253

z-VAD-fmk

Pan caspase inhibitor

z-VAD-fmk (Z-VAD(OH)-FMK) is a well-known small molecule pan-caspase inhibitor.

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