| Cat. No. |
Product Name |
Information |
| PC-43410 |
BOC-D-FMK
|
BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM. |
| PC-43391 |
VX-765
|
VX-765 (Belnacasan) is an orally absorbed prodrug of VRT-043198, which is a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 with Ki of 0.8 nM. |
| PC-43046 |
Z-DEVD-FMK
|
Z-DEVD-FMK is a specific caspase-3 inhibitor with IC50 of 18 uM. |
| PC-62211 |
WF-210
|
WF-210 is a PAC-1 derivative and potent activator of procaspases-3 with EC50 of 0.95 uM, displays more cytotoxic than PAC‐1 to human cancer cells, but less cytotoxic to normal cells. |
| PC-62210 |
Procaspase-3 activator 1541B
|
Procaspase-3 activator 1541B is a specific, small molecule activator of procaspases-3 with EC50 of 1.3 uM. |
| PC-62209 |
Procaspase-3 activator 1541
|
Procaspase-3 activator 1541 is a small-molecule inducer of cell death that noncovalently self-assembles into chemical fibrils and activates procaspase-3 and 6 in vitro (EC50=2.4 and 2.8 uM). |
| PC-61354 |
IDN-7314
|
A potent, orally active, and irreversible pan-Caspase protease inhibitor with IC50 of <0.08 to 7 nM for inhibition of activated caspase 3, 6 and 8. |
| PC-70208 |
NWL-117
|
A potent Caspase-6 inhibitor with IC50 of 192 nM, also inhibits Caspase-4/8/9/10 with IC50 of 0.1-0.8 uM. |
