Emricasan (IDN-6556, PF-03491390)

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Chemical Structure : Emricasan

CAS No.: 254750-02-2

Catalog No.: PC-62433Not For Human Use, Lab Use Only.

Emricasan (IDN-6556, PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.

Packing	Price	Stock
5 mg	$98	In stock
10 mg	$148	In stock
50 mg	$358	In stock
100 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Emricasan (IDN-6556, PF-03491390) is a potent, irreversible pan-caspase inhibitor, shows neuroprotective activity for hNPCs, inhibits ZIKV-induced increased caspase-3 activity.

Physicochemical Properties

M.Wt	569.51
Formula	C26H27F4N3O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid

References

1. Xu M, et al. Nat Med. 2016 Oct;22(10):1101-1107.

2. Brumatti G, et al. Sci Transl Med. 2016 May 18;8(339):339ra69.

3. McCall MD, et al. Transplantation. 2012 Jul 15;94(1):30-5.

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