| Cat. No. |
Product Name |
Information |
| PC-22752 |
Ac-YVAD-cmk
Caspase-1 inhibitor
|
Ac-YVAD-cmk is a tetrapeptide, selective caspase-1 (interleukin-1 beta converting enzyme, ICE) inhibitor with neuroprotective and anti-inflammatory effects, inhibits pyroptosis (caspase-1-activated cell death). |
| PC-22751 |
Z-YVAD-FMK
Caspase-1 inhibitor
|
Z-YVAD-FMK is a specific, cell-permeable and irreversible caspase-1 inhibitor with anti-inflammatory and anti-tumor activities. |
| PC-22740 |
PAC-1
Procaspase-3 activator
|
PAC-1 (Procaspase activating compound 1) is a small-molecule activator of procaspase-3 to caspase-3, induces apoptosis in cancerous cells, induces apoptosis in HL-60 cells with EC50 of 2.08 uM. |
| PC-22034 |
CZL80
Caspase-1 inhibitor
|
Caspase-1 inhibitor CZL80 is a potent, selective, brain-penetrable Caspase-1 inhibitor with IC50 of 0.01 uM. |
| PC-49742 |
NS3694
Caspase inhibitor
|
NS3694 (NS 3694) is a specific cell-permeable diarylurea compound that inhibits apoptosome formation and caspase activation, blocks cytochrome c-induced caspase activation in HeLa cell cytosolic extracts with IC50 of 50 uM. |
| PC-73051 |
Procaspase-6 inhibitor 13
Procaspase-6 inhibitor
|
Procaspase-6 inhibitor 13 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.38 uM. |
| PC-73050 |
Procaspase-6 inhibitor 12
Procaspase-6 inhibitor
|
Procaspase-6 inhibitor 12 is a small molecule, noncovalent, allosteric inhibitor of procaspase-6 with KD of 0.47 uM. |
| PC-73049 |
PG3d
Caspase-6 inhibitor
|
PG3d (Caspase-6 inhibitor PG3d) is a cell-active, allosteric and irreversible, non-competitive Caspase-6 inhibitor. |
| PC-72960 |
NH-23-C2
Caspase-2 inhibitor
|
NH-23-C2 (Caspase-2 inhibitor NH-23-C2) is a potent, selective and cell-permeable endogenous caspase-2 inhibitor, does not block caspase-3 or caspase-8. |
| PC-35176 |
Ac-IEPD-CHO
Granzyme B inhibitor
|
Ac-IEPD-CHO (Ac-Ile-Glu-Pro-Asp-CHO) is a potent, reversible inhibitor of serine protease Granzyme B (GzmB) with Ki of 80 nM, also inhibits caspase-7 (Ki=550 nM) and induces apoptosis. |
| PC-63279 |
ML132
Caspase-1 inhibitor
|
ML132 (NCGC00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases. |
| PC-43410 |
BOC-D-FMK
Caspase inhibitor
|
BOC-D-FMK is a cell-permeable, irreversible, broad spectrum caspase inhibitor, inhibits apoptosis stimulated by TNF-α with IC50 of 39 uM. |
