Chemical Structure : z-LEHD-FMK
CAS No.: 210345-04-3
Catalog No.: PC-24251Not For Human Use, Lab Use Only.
z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis, exhibits the neuroprotective effect in rat model of spinal cord trauma.
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z-LEHD-FMK is a selective and irreversible inhibitor of caspase-9, protects against lethal reperfusion injury and attenuates apoptosis, exhibits the neuroprotective effect in rat model of spinal cord trauma.
| M.Wt | 690.73 | |
| Formula | C32H43FN6O10 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Methyl (5S,8S,11S,14S)-11-((1H-imidazol-5-yl)methyl)-14-(2-fluoroacetyl)-5-isobutyl-8-(3-methoxy-3-oxopropyl)-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazahexadecan-16-oate |
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1. Xiao Y, et al. J Pharmacol Exp Ther. 2000 Jan;292(1):8-14.
2. Ozoren N, et, al. Cancer Res. 2000 Nov 15; 60(22): 6259-65.
3. Mocanu MM, et, al. Br J Pharmacol. 2000 May; 130(2): 197-200.

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