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MMPSI

Chemical Structure : MMPSI

CAS No.: 220509-74-0

MMPSI (Caspase 3/7 inhibitor MPS)

Catalog No.: PC-24912Not For Human Use, Lab Use Only.

MMPSI is a potent and selective, non-peptide caspase 3/7 inhibitor with Ki app of 0.06 uM and 0.17 uM respective, exhibits >100-fold selectivity over all other family members except caspase 9 (Ki app=3.1 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MMPSI is a potent and selective, non-peptide caspase 3/7 inhibitor with Ki app of 0.06 uM and 0.17 uM respective, exhibits >100-fold selectivity over all other family members except caspase 9 (Ki app=3.1 uM).

Physicochemical Properties

M.Wt 324.35
Formula C14H16N2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-5-((2-(Methoxymethyl)pyrrolidin-1-yl)sulfonyl)indoline-2,3-dione

References

1. Chapman JG, et al, Eur J Pharmacol. 2002;456(1-3):59-68.

2. Lee D, et al. J Biol Chem. 2000 May 26;275(21):16007-14.

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