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Ac-LETD-CHO

Chemical Structure : Ac-LETD-CHO

CAS No.:

Ac-LETD-CHO (Ac-Leu-Glu-Thr-Asp-CHO)

Catalog No.: PC-28007Not For Human Use, Lab Use Only.

Ac-LETD-CHO is a specific caspase-8 inhibitor with IC50 of 6.71 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Ac-LETD-CHO is a specific caspase-8 inhibitor with IC50 of 6.71 nM.

Physicochemical Properties

M.Wt 502.52
Formula C21H34N4O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4S,7S,10S,13S)-7-(2-carboxyethyl)-13-formyl-10-((R)-1-hydroxyethyl)-4-isobutyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid

References

1. Hu J, et al. Angew Chem Int Ed Engl. 2016 Jun 1;55(23):6667-70.

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