Chemical Structure : VRT-043198
CAS No.: 244133-31-1
Catalog No.: PC-28002Not For Human Use, Lab Use Only.
VRT-043198 is the active metabolite of Belnacasan (VX-765), which is a potent, selective and blood-brain barrier permeable inhibitor of interleukin-converting enzyme/caspase-1, exhibits Ki of 0.8 nM and 0.6 nM for ICE/Caspase-1 and Caspase-4, respectively.
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|---|---|---|---|
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| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
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VRT-043198 is the active metabolite of Belnacasan (VX-765), which is a potent, selective and blood-brain barrier permeable inhibitor of interleukin-converting enzyme/Caspase-1, exhibits Ki of 0.8 nM and 0.6 nM for ICE/Caspase-1 and Caspase-4, respectively.
| M.Wt | 480.95 | |
| Formula | C22H29ClN4O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-3-((S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-4-oxobutanoic acid |
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1. Woods Wannamaker, et al. J Pharmacol Exp Ther. 2007 May;321(2):509-16.

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