Ac-YVAD-CHO (L-709049) | Caspase-1 inhibitor

Chemical Structure : Ac-YVAD-CHO

CAS No.: 143313-51-3

Ac-YVAD-CHO (L-709049, L709049)

Catalog No.: PC-26489Not For Human Use, Lab Use Only.

Ac-YVAD-CHO (L-709049) is a potent, reversible, specific tetrapeptide interleukin-1β converting enzyme (ICE, Caspase-1) inhibitor with Ki values of 3.0 and 0.76 nM mouse and human caspase-1, suppresses the production of mature IL-lβ.

Packing	Price	Stock
5 mg	$258	In stock
10 mg	$398	In stock
25 mg	$598	In stock
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Biological Activity

Ac-YVAD-CHO (L-709049) is a potent, reversible, specific tetrapeptide interleukin-1β converting enzyme (ICE, Caspase-1) inhibitor with Ki values of 3.0 and 0.76 nM mouse and human caspase-1, suppresses the production of mature IL-lβ.

Physicochemical Properties

M.Wt	492.53
Formula	C23H32N4O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ac-Tyr-Val-Ala-Asp-aldehyde

References

1. Fletcher DS, et al. J Interferon Cytokine Res. 1995;15(3):243-248.

2. Zhou X, et al. J Immunol. 2000 Aug 1;165(3):1252-8.

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Ac-YVAD-CHO (L-709049, L709049)

Biological Activity

Physicochemical Properties

References

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