Saikosaponin C

Chemical Structure : Saikosaponin C

CAS No.: 20736-08-7

Catalog No.: PC-27754Not For Human Use, Lab Use Only.

Saikosaponin C is a natural compound purified from the traditional Chinese herb of Radix Bupleuri, exhibits anti-HBV replication activity and inhibits by targeting HNF1α and HNF4αHBV pgRNA synthesis, significantly inhibits LPS-induced apoptotic cell death in HUVECs via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.

Packing	Price	Stock
10 mg	$98	In stock
25 mg	$158	In stock
50 mg	$258	In stock
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Biological Activity

Saikosaponin C is a natural compound purified from the traditional Chinese herb of Radix Bupleuri, exhibits anti-HBV replication activity and inhibits by targeting HNF1α and HNF4αHBV pgRNA synthesis, significantly inhibits LPS-induced apoptotic cell death in HUVECs via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.

Physicochemical Properties

M.Wt	927.14
Formula	C48H78O17
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3R,4R,5R,6S)-2-(((2R,3S,4R,5R,6R)-4,5-Dihydroxy-6-(((3S,4aR,6aR,6bS,8S,8aS,12aR,12bS,14aR,14bS)-8-hydroxy-4,4,6a,6b,11,11,14b-heptamethyl-2,3,4,4a,5,6,6a,6b,7,8,10,11,12,12a,14a,14b-hexadecahydro-1H,9H-12b,8a-(epoxymethano)picen-3-yl)oxy)-2-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol

References

1. Deng C, et al. J Ethnopharmacol. 2025 Sep 25;353(Pt A):120283.

2. Chen D, et al. J Ethnopharmacol. 2025 Aug 29;352:120221.

3. Pan Y, et al. Inflamm Res. 2019 Dec;68(12):1025-1034.

4. Lee TH, et al. Biochem Biophys Res Commun. 2014 Mar 14;445(3):615-21.

Saikosaponin C

Biological Activity

Physicochemical Properties

References

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