Chemical Structure : Ac-DEVD-CHO
CAS No.:
169332-60-9
Ac-DEVD-CHO
(Acetyl-Asp-Glu-Val-Asp-aldehyde)
Catalog No. : PC-26675Not For Human Use, Lab Use Only.
Ac-DEVD-CHO is a specific inhibitor of apoptosis and reversible caspase-3 inhibitor with Ki of 0.23 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2667501
Biological Activity
Ac-DEVD-CHO is a specific inhibitor of apoptosis and reversible caspase-3 inhibitor with Ki of 0.23 nM.
Physicochemical Properties
M.Wt
502.48
Formula
C20H30N4O11
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(4S,7S,10S,13S)-7-(2-Carboxyethyl)-4-(carboxymethyl)-13-formyl-10-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
References
1. Garcia-Calvo M, et al.nhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13.
2. Jinglin Wang, et al. A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice. Oncotarget. 2017 Jan 3; 8(1): 610-623.
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