ML132 |CAS:1230628-71-3 Probechem Biochemicals

Chemical Structure : ML132

CAS No.: 1230628-71-3

ML132 (NCGC-00183434;CID-4462093)

Catalog No.: PC-63279Not For Human Use, Lab Use Only.

ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases..

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Biological Activity

ML132 (NCGC-00183434, CID-4462093) is a highly potent, selective Caspase 1 inhibitor with IC50 of 0.023 nM, displays >1,000-fold selectivity over a panel of 9 caspases.

Physicochemical Properties

M.Wt	477.941
Formula	C22H28ClN5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-3-((S)-1-((S)-2-(4-amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)pyrrolidine-2-carboxamido)-3-cyanopropanoic acid

References

1. Boxer MB, et al. A small molecule inhibitor of Caspase 1. Probe Reports from the NIH Molecular Libraries Program [Internet].

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ML132 (NCGC-00183434;CID-4462093)

Biological Activity

Physicochemical Properties

References

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