Ac-YVAD-cmk | Caspase-1 inhibitor | Probechem Biochemicals

Chemical Structure : Ac-YVAD-cmk

CAS No.: 178603-78-6

Ac-YVAD-cmk (Ac-YVAD-chloromethylketone, Caspase-1 inhibitor)

Catalog No.: PC-22752Not For Human Use, Lab Use Only.

Ac-YVAD-cmk is a tetrapeptide, selective caspase-1 (interleukin-1 beta converting enzyme, ICE) inhibitor with neuroprotective and anti-inflammatory effects, inhibits pyroptosis (caspase-1-activated cell death).

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5 mg	$238	In stock
10 mg	$388	In stock
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Biological Activity

Physicochemical Properties

M.Wt	541.00
Formula	C24H33ClN4O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-Acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-alaninamide

References

1. Dubrez L, et al. EMBO J. 1996 Oct 15;15(20):5504-12.

2. Yang M, et al. Biomed Res Int. 2021 Jun 10;2021:6636621.

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Ac-YVAD-cmk (Ac-YVAD-chloromethylketone, Caspase-1 inhibitor)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

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