You are here:Home-Chemical Inhibitors & Agonists-Apoptosis-Caspase-Ac-YVAD-cmk
Ac-YVAD-cmk

Chemical Structure : Ac-YVAD-cmk

CAS No.: 178603-78-6

Ac-YVAD-cmk (Ac-YVAD-chloromethylketone, Caspase-1 inhibitor)

Catalog No.: PC-22752Not For Human Use, Lab Use Only.

Ac-YVAD-cmk is a tetrapeptide, selective caspase-1 (interleukin-1 beta converting enzyme, ICE) inhibitor with neuroprotective and anti-inflammatory effects, inhibits pyroptosis (caspase-1-activated cell death).

Packing Price Stock Quantity
5 mg $238 In stock
10 mg $388 In stock
25 mg Get quote
50 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Ac-YVAD-cmk is a tetrapeptide, selective caspase-1 (interleukin-1 beta converting enzyme, ICE) inhibitor with neuroprotective and anti-inflammatory effects, inhibits pyroptosis (caspase-1-activated cell death).

Physicochemical Properties

M.Wt 541.00
Formula C24H33ClN4O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-Acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-alaninamide

References

1. Dubrez L, et al. EMBO J. 1996 Oct 15;15(20):5504-12.

2. Yang M, et al. Biomed Res Int. 2021 Jun 10;2021:6636621.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: