| Cat. No. |
Product Name |
Information |
| PC-38281 |
P2119
Spike RBD-ACE2 inhibitor
|
P2119 (P-2119) is an anticoronaviruse chemical probe that inhibit SARS-CoV-2 Spike binding to human ACE2 receptor. |
| PC-38259 |
MM3122
TMPRSS2 inhibitor
|
MM3122 (MM-3122) is a selective inhibitor of host cell serine protease TMPRSS2 with IC50 of 0.34 nM against recombinant full-length TMPRSS2 protein. |
| PC-38238 |
DX600
ACE2 inhibitor
|
DX600 (DX-600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM. |
| PC-38237 |
MU-UNMC-2
Spike RBD-ACE2 inhibitor
|
MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells. |
| PC-38236 |
MU-UNMC-1
Spike RBD-ACE2 inhibitor
|
MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells. |
| PC-38235 |
SB27012
Spike RBD-ACE2 inhibitor
|
SB27012 (SB 27012) is a small molecule PPI inhibitor of the Spike RBD-ACE2 interaction (IC50=7.7 uM in ELISA assays), binds ACE2 (Kd=210 nM) without affecting ACE2 enzymatic activity. |
| PC-38178 |
Ensitrelvir
3CLpro inhibitor
|
Ensitrelvir (S-217622, S217622) is the first oral, non-covalent, non-peptidic SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate with biochemical IC50 of 13 nM, antiviral EC50 of 0.37 uM. |
| PC-35231 |
GC376
3CLpro inhibitor
|
GC376 (GC-376) is a broad-spectrum antiviral agent that inhibits 3C or 3C-like proteases (3Cpro or 3CLpro) of picornaviruses, noroviruses, and coronaviruses with IC50 of 0.96 (MD145), 0.82 (TGEV) and 0.2 uM (HRV) in FRET protease assays. |
| PC-27892 |
mCMX110
SARS-CoV-2 Mpro inhibitor
|
mCMX110 is a potent, selective, orally bioavailable SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 35 nM. |
| PC-26986 |
ACE2 inhibitor MB-32
ACE2 inhibitor
|
MB‑32 is a specific, allosteric inhibitor of angiotensin‑converting enzyme 2 (ACE2) with KD of 7.078 and 3.997 uM in SPR and BLI assays, selectively disrupts binding of SARS‑CoV‑2 spike receptor‑binding domain to ACE2, MB-32 is a potent and specific broad-spectrum entry inhibitor of pan-sarbecoviruses. |
| PC-26746 |
CG-0988
SARS-CoV-2 3CLpro inhibitor
|
CG-0988 is a potent, covalent SARS-CoV-2 3C-like protease (3CLpro) inhibitor with IC50 of 8.5 nM, demonstrates excellent antiviral activity with EC50 of 4.0 nM against Omicron EG.5.1. |
| PC-26549 |
SARS-CoV-2 entry inhibitor S22
RBD-ACE2 inhibitor
|
SARS-CoV-2 entry inhibitor S22 is a potent, SARS-CoV-2-specific entry inhibitor that neutralizes BA.2 and subsequent Omicron variants, blocks RBD-ACE2 interaction. |
