| Cat. No. |
Product Name |
Information |
| PC-22224 |
Mpro61
SARS-CoV-2 Mpro inhibitor
|
Mpro61 is a potent nanomolar inhibitor of SARS-CoV-2 Mpro with IC50 of 44 nM, antiviral EC50 of 80 nM. |
| PC-22009 |
ML2006a4
SARS-CoV-2 Mpro inhibitor
|
ML2006a4 is a highly potent, selective and orally bioavailable SARS-CoV-2 main protease (Mpro) inhibitor with IC50/Ki of 1.05/0.26 nM, shows antiviral EC50 value of 100-120 nM in Huh7.5.1-ACE2-TMPRSS2 cells. |
| PC-21878 |
GC-373
SARS-CoV-2 Mpro inhibitor
|
GC373 is a potent, covalent inhibitor of SARS CoV-2 main protease (MPro) with Kd of 0.15 uM, the reactive aldehyde form of GC376. |
| PC-21803 |
MK-7845
SARS-CoV-2 3CLPro inhibitor
|
MK-7845 is a potent, reversible covalent SARS-CoV-2 3CLPro inhibitor with IC50 of 8.7 nM, inhibits wild-type SARS-CoV-2 3CLPro in SARS-CoV-2 reporter replicon assay in A549 cells with IC50 of 15 nM. |
| PC-21690 |
MDOLL-0229
SARS-CoV-2 Mac1 inhibitor
|
MDOLL-0229 is a selective small molecule inhibitor for SARS-CoV-2 Mac1 with IC50 of 2.1 uM, inhibits coronavirus replication. |
| PC-21479 |
JC19
SARS-CoV-2 nsp14 degrader
|
JC19 is a a cysteine-reactive small molecule degrader of SARS-CoV-2 nsp14 with DC50 of 8.7 uM in HEK293T cells. |
| PC-21451 |
GC-78-HCl
SARS-CoV-2 Mpro inhibitor
|
GC-78-HCl is a potent nonpeptide SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.19 uM, exhibits excellent antiviral activity (EC50=0.4 uM). |
| PC-21419 |
Compound 212-148
TMPRSS2 inhibitor
|
Compound 212-148 a bispecific, dual inhibitor of both TMPRSS2 and cysteine proteases cathepsin L/B (CTSL/CTSB) with IC50 of 1.38 uM and 2.13/64.07 nM, respectively, demonstrates antiviral activity against various SARS-CoV-2 variants. |
| PC-21119 |
D-4-77
SARS-CoV-2 Mpro inhibitor
|
D-4-77 is a potent, covalent peptidyl inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 0.95 uM and antiviral EC50 of 0.49 uM. |
| PC-21016 |
SARS-CoV-2 3CLpro inhibitor C5a
SARS-CoV-2 3CLpro inhibitor
|
SARS-CoV-2 3CLpro inhibitor C5a is a potent, non-covalent, non-peptide inhibitor of 3C-like protease (3CLpro) inhibitor with dissociation constant (Kd) of 170 nM, IC50 of 0.7 uM against recombinant SARS-CoV-2 3CLpro. |
| PC-20951 |
NACE2i
ACE2 inhibitor
|
NACE2i is a cell permeable, specific and selective peptide inhibitor of nuclear ACE2, inhibits binding between IMP1α and ACE2 and SARS-CoV-2 viral replication. |
| PC-20900 |
PAV-104
SARS-CoV-2 assembly inhibitor
|
PAV-104 (PAV104) is a novel viral assembly inhibitor, shows potent anti-SARS-CoV-2 activity in Calu-3 cells with EC50 of 1.7 nM and EC90 of 23.5 nM, inhibits the oligomerization of the SARS-CoV-2 nucleocapsid. |
