| Cat. No. |
Product Name |
Information |
| PC-23632 |
TDI-015051
SARS-CoV-2 NSP14 inhibitor
|
TDI-015051 is a highly potent, specific inhibitor of SARS-CoV-2 NSP14 RNA cap methyltransferase with Kd of 61 pM and IC50 of <0.15 nM, inhibits viral mRNA translation. |
| PC-23359 |
SHEN26
SARS-CoV-2 RdRp inhibitor
|
Losudesivir (SHEN26, ATV014) is a potent, orally active anti-SARS-CoV-2 nucleoside compound with EC50 of 0.48 uM against SARS-CoV-2 replicon, inhibits SARS-CoV-2 RdRp. |
| PC-22947 |
AVI-4206
SARS-CoV-2 Mac1 inhibitor
|
AVI-4206 is a potent, specific small molecule inhibitor of SARS-CoV-2 ADP-ribosylhydrolase macrodomain (Mac1) with IC50 of 20 nM in HTRF assays. |
| PC-22802 |
EDP-235
3CLpro inhibitor
|
EDP-235 (Zevotrelvir, EDP235) is a potent, selective inhibitor of SARS-CoV-2 3CLpro with IC50 of 4.0 nM, Kiapp of 3.0 nM, reversibly binds and inhibits the 3CLpro. |
| PC-22547 |
Virapinib
Macropinocytosis inhibitor
|
Virapinib is a specific inhibitor of macropinocytosis with antiviral activity, limits viral entry by macropinocytosis for several viruses including SARS-CoV-2. |
| PC-22258 |
Ibuzatrelvir
SARS-CoV-2 Mpro inhibitor
|
Ibuzatrelvir (PF-07817883) is a second-generation, orally bioavailable, SARS-CoV-2 main protease (Mpro) with Ki value of 2.48 nM, EC50 of 180 nM for inhibition of SARS-CoV-2 induced cytopathic effect (CPE). |
| PC-22224 |
Mpro61
SARS-CoV-2 Mpro inhibitor
|
Mpro61 is is a potent, selective, noncovalent and nonpeptidomimetic inhibitor of SARS-CoV-2 Mpro with Ki of 72 nM, 83 nM and 92 nM for WT Mpro and A173V and A173V/L50F variants respectively. |
| PC-22071 |
Leritrelvir
SARS-CoV-2 Mpro inhibitor
|
Leritrelvir (RAY1216) is a potent, selective peptidomimetic inhibitor of SARS-CoV-2 main protease (Mpro) with Ki of 8.4 nM. |
| PC-21878 |
GC373
SARS-CoV-2 Mpro inhibitor
|
GC373 is a potent, covalent inhibitor of SARS CoV-2 main protease (MPro) with Kd of 0.15 uM, the reactive aldehyde form of GC376. |
| PC-21780 |
CMX990
SARS-CoV-2 3CLpro inhibitor
|
CMX990 is a potent, selective and covalent SARS-CoV-2 3CLpro inhibitor with IC50 of 23.4 nM, exhibits good potency (EC50=37 nM) in HeLa-ACE2 SARS-CoV-2 assays. |
| PC-21710 |
AC1115
SARS-CoV-2 Mpro inhibitor
|
AC1115 is a potent, selective, next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, AC1115 is the active form of Olgotrelvir. |
| PC-21709 |
Olgotrelvir
SARS-CoV-2 Mpro inhibitor
|
Olgotrelvir (STI-1558) is a next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, Olgotrelvir is the prodrug of AC1115. |
