GS-5245 (Obeldesivir, ATV006) | Antiviral

Chemical Structure : GS-5245

CAS No.: 2647441-36-7

GS-5245 (Obeldesivir, GS 5245, ATV006)

Catalog No.: PC-21075Not For Human Use, Lab Use Only.

GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo.

Packing	Price	Stock
5 mg	$158	In stock
10 mg	$248	In stock
25 mg	$398	In stock
50 mg	$588	In stock
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Biological Activity

GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo.

Physicochemical Properties

M.Wt	361.36
Formula	C16H19N5O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl isobutyrate

References

1. Richard L. Mackman, et al. J. Med. Chem. 2023.
2. Cao L, et, al. Sci Transl Med. 2022 May 17:eabm7621.

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GS-5245 (Obeldesivir, GS 5245, ATV006)

Biological Activity

Physicochemical Properties

References

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