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GS-5245

Chemical Structure : GS-5245

CAS No.: 2647441-36-7

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GS-5245 (Obeldesivir, GS 5245, ATV006)

Catalog No.: PC-21075Not For Human Use, Lab Use Only.

GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo.

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5 mg $158 In stock
10 mg $248 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo.

Physicochemical Properties

M.Wt 361.36
Formula C16H19N5O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl isobutyrate

References

1. Richard L. Mackman, et al. J. Med. Chem. 2023.
2. Cao L, et, al. Sci Transl Med. 2022 May 17:eabm7621.

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