| Cat. No. |
Product Name |
Information |
| PC-38696 |
Y180
SARS-CoV-2 Mpro inhibitor
|
Y180 is a highly potent, selective, covalent, and orally active SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 8.1 nM in enzymatic assays, binding Ki value of 1 nM. |
| PC-38568 |
SSAA09E3
SARS CoV entry inhibitor
|
SSAA09E3 is a small molecule inhibitor of SARS coronavirus with EC50 of 0.15 uM in infectious virus assay in Vero cells, preventing fusion of the viral membrane with the host cellular membrane. |
| PC-38498 |
SARS-CoV-2 nsp14 inhibitor 25
SARS-CoV-2 nsp14 inhibitor
|
SARS-CoV-2 nsp14 inhibitor 25 is a highly potent, selective, nucleoside-derived inhibitor of SARS-CoV-2 nsp14 (N7-guanine)-methyltransferase (N7-MTase) with IC50 of 19 nM, no inhibition against human RNA N7-MTase (hRNMT, IC50>50 uM). |
| PC-38459 |
GS-621763
SARS-CoV-2 Inhibitor
|
GS-621763 is an oral prodrug of remdesivir parent nucleoside GS-441524, inhibits SARS-CoV-2, including variants of concern in cell culture (EC50=0.11 to 0.73 uM) and human airway epithelium organoids. |
| PC-73461 |
Molnupiravir
SARS-CoV-2 inhibitor
|
EIDD-2801 (MK-4482, Molnupiravir) is a highly potent ribonucleoside analog, and prodrug of EIDD-1931, exhibits broad-spectrum antiviral inhibitor of multiple RNA viruses including SARS-CoV-2. |
| PC-73344 |
Pin1 inhibitor H-77
Pin1 inhibitor
|
Pin1 inhibitor H-77 (H-77) is a small molecule Pin1 inhibitor that blocks SARS-CoV-2 proliferation with EC50 of 3.2 uM. |
| PC-73341 |
Coronastat
SARS-CoV-2 3CLpro inhibitor
|
Coranastat (NK01-63) is a GC376 analog with improved potency, and highly potent, selective SARS-CoV-2 3CL protease inhibitor with IC50 of 16 nM, exhibits antiviral potency with EC50 of 6 nM in Huh-7ACE2 cellular assays. |
| PC-73340 |
MAC-5576
SARS-CoV-2 3CLpro inhibitor
|
MAC-5576 (MAC5576) is a small molecule, covalent inhibitor of coronavirus SARS-CoV 3CLpro with IC50 of 0.5 uM, inhibits SARS-CoV-2 3CL protease with IC50 of 0.093 uM. |
| PC-73233 |
SSAA09E2
Spike-ACE2 inhibitor
|
SSAA09E2 is a small molecule inhibitor of SARS entry, blcks early interactions of SARS-CoV surface glycoprotein S (SARS-S) with angiotensin converting enzyme 2 (ACE2), also inhibits SARS-CoV-2 Spike-ACE2 interaction. |
| PC-73166 |
Molnupiravir N-1
Molnupiravir Impurity
|
Molnupiravir N-1 is an impurity chemical of Molnupiravir (EIDD-2801, MK4482), which is anti-SARS-CoV-2 for treatment of COVID-19. |
| PC-73013 |
Z222979552
SARS-CoV-2 Mpro inhibitor
|
Z222979552 is a small molecule non-covalent SARS-CoV-2 Mpro inhibitor with IC50 of 1.0 uM. |
| PC-72893 |
(S)-chlorcyclizine
SARS CoV fusion inhibitor
|
(S)-chlorcyclizine ((S)-CCZ) is an approved antihistamine drug that is related to dichlorcyclizine (DCCZ), inhibits SARS-CoV and SARS-CoV-2 S-mediated infection in MA104 cells with EC50 of 6.91 and 4.09 uM. |
