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DMGA

Chemical Structure : DMGA

CAS No.: 17339-60-5

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DMGA

Catalog No.: PC-49528Not For Human Use, Lab Use Only.

DMGA is an allosteric and covalent inhibitor of SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro) with IC50 of 9.4 uM, covalently binds with C270 of the SARS-CoV-2 PLpro.

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50 mg $198 In stock
100 mg $298 In stock
500 mg $498 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

DMGA is an allosteric and covalent inhibitor of SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro) with IC50 of 9.4 uM, covalently binds with C270 of the SARS-CoV-2 PLpro.

Physicochemical Properties

M.Wt 281.30
Formula C8H22Cl2N2S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ethanamine, 2,2′-dithiobis[N,N-dimethyl-, hydrochloride (1:2)

References

1. Hangchen Hu, et al. Angew Chem Int Ed Engl. 2022 Oct 29. doi: 10.1002/anie.202212378.

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