Cat. No. |
Product Name |
Information |
PC-49424 |
Difluorobenztropine
|
Difluorobenztropine (AHN 1-055) is a direct-acting SARS-CoV-2 entry inhibitor that targets the SARS-CoV-2 spike fusion peptide domain. |
PC-49423 |
TMPRSS2 inhibitor BC-11
TMPRSS2 inhibitor
|
TMPRSS2 inhibitor BC-11 is a specific, covalent transmembrane protease serine 2 (TMPRSS2) inhibitor with IC50 of 1.44 uM in vitro TMPRSS2 enzymatic assay. |
PC-49342 |
GC-14
SARS-CoV-2 Mpro inhibitor
|
GC-14 is a potent, selective and non-covalent non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.4 uM, displays excellent selectivity over cathepsins B, F, K, L, and caspase 3 (IC50>50 uM). |
PC-49335 |
WU-04
3CLpro inhibitor
|
WU-04 is a highly potent, non-covalent, orally active inhibitor of SARS-CoV-2 3C-like protease (3CLpro) with IC50 of 72 nM, binding Kd of 37 nM. |
PC-49327 |
KSL 128114
Syntenin inhibitor
|
KSL-128114 (KLS 128114) is a highly potent and metabolically stable peptide inhibitor that binds to the PDZ1 domain of syntenin (KD=0.3 uM), inhibits SARS-CoV-2 infection by blocking the endosomal entry of the virus. |
PC-49258 |
AB-00011778
SARS-CoV-2 entry inhibitor
|
AB-00011778 is a small molecule inhibitor of SARS-CoV-2 entry and the Spike/ACE2 interaction, inhibits viral replication with EC50 of 250 nM in A549-ACE2 cells, AB-00011778 is equally effective in impairing the S/ACE2 association in the different mutants. |
PC-47020 |
Nafamostat mesylate
SARS-CoV-2 Inhibitor
|
Nafamostat mesylate is a synthetic serine protease inhibitor with anticoagulant, anti-inflammatory, mucus clearing, and potential antiviral activities, blocked SARS-CoV-2 infection of Calu-3 cells with IC50 of 10 nM. |
PC-38897 |
VE607
SARS-CoV entry inhibitor
|
VE607 is a specific small molecule inhibitor that block S protein-ACE2-mediated cellular entry of the SARS-CoV, inhibits pseudovirus entry with EC50 of 3 μM and inhibited SARS-CoV plaque formation with EC50 of 1.6 μM. |
PC-38708 |
ALG-097111
SARS-CoV-2 3CLpro inhibitor
|
ALG-097111 is a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease (3CLpro) with IC50 of 7 nM, without effect against human cathepsin L (IC50>10 uM). |
PC-38696 |
Y180
SARS-CoV-2 Mpro inhibitor
|
Y180 is a highly potent, selective, covalent, and orally active SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 8.1 nM in enzymatic assays, binding Ki value of 1 nM. |
PC-38568 |
SSAA09E3
SARS CoV entry inhibitor
|
SSAA09E3 is a small molecule inhibitor of SARS coronavirus with EC50 of 0.15 uM in infectious virus assay in Vero cells, preventing fusion of the viral membrane with the host cellular membrane. |
PC-73344 |
Pin1 inhibitor H-77
Pin1 inhibitor
|
Pin1 inhibitor H-77 (H-77) is a small molecule Pin1 inhibitor that blocks SARS-CoV-2 proliferation with EC50 of 3.2 uM. |