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Cat. No. Product Name Information
PC-49424

Difluorobenztropine

Difluorobenztropine (AHN 1-055) is a direct-acting SARS-CoV-2 entry inhibitor that targets the SARS-CoV-2 spike fusion peptide domain.
PC-49423

TMPRSS2 inhibitor BC-11

TMPRSS2 inhibitor

TMPRSS2 inhibitor BC-11 is a specific, covalent transmembrane protease serine 2 (TMPRSS2) inhibitor with IC50 of 1.44 uM in vitro TMPRSS2 enzymatic assay.
PC-49342

GC-14

SARS-CoV-2 Mpro inhibitor

GC-14 is a potent, selective and non-covalent non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.4 uM, displays excellent selectivity over cathepsins B, F, K, L, and caspase 3 (IC50>50 uM).
PC-49335

WU-04

3CLpro inhibitor

WU-04 is a highly potent, non-covalent, orally active inhibitor of SARS-CoV-2 3C-like protease (3CLpro) with IC50 of 72 nM, binding Kd of 37 nM.
PC-49327

KSL 128114

Syntenin inhibitor

KSL-128114 (KLS 128114) is a highly potent and metabolically stable peptide inhibitor that binds to the PDZ1 domain of syntenin (KD=0.3 uM), inhibits SARS-CoV-2 infection by blocking the endosomal entry of the virus.
PC-49258

AB-00011778

SARS-CoV-2 entry inhibitor

AB-00011778 is a small molecule inhibitor of SARS-CoV-2 entry and the Spike/ACE2 interaction, inhibits viral replication with EC50 of 250 nM in A549-ACE2 cells, AB-00011778 is equally effective in impairing the S/ACE2 association in the different mutants.
PC-47020

Nafamostat mesylate

SARS-CoV-2 Inhibitor

Nafamostat mesylate is a synthetic serine protease inhibitor with anticoagulant, anti-inflammatory, mucus clearing, and potential antiviral activities, blocked SARS-CoV-2 infection of Calu-3 cells with IC50 of 10 nM.
PC-38897

VE607

SARS-CoV entry inhibitor

VE607 is a specific small molecule inhibitor that block S protein-ACE2-mediated cellular entry of the SARS-CoV, inhibits pseudovirus entry with EC50 of 3 μM and inhibited SARS-CoV plaque formation with EC50 of 1.6 μM.
PC-38708

ALG-097111

SARS-CoV-2 3CLpro inhibitor

ALG-097111 is a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease (3CLpro) with IC50 of 7 nM, without effect against human cathepsin L (IC50>10 uM).
PC-38696

Y180

SARS-CoV-2 Mpro inhibitor

Y180 is a highly potent, selective, covalent, and orally active SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 8.1 nM in enzymatic assays, binding Ki value of 1 nM.
PC-38568

SSAA09E3

SARS CoV entry inhibitor

SSAA09E3 is a small molecule inhibitor of SARS coronavirus with EC50 of 0.15 uM in infectious virus assay in Vero cells, preventing fusion of the viral membrane with the host cellular membrane.
PC-73344

Pin1 inhibitor H-77

Pin1 inhibitor

Pin1 inhibitor H-77 (H-77) is a small molecule Pin1 inhibitor that blocks SARS-CoV-2 proliferation with EC50 of 3.2 uM.

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