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Chemical Structure : NSC 621601
Catalog No.: PC-72328Not For Human Use, Lab Use Only.
NSC 621601 (Compound Q34) is a potent, specific inhibitor of SARS-CoV-2 cellular entry with IC50 of 15 uM.
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NSC 621601 (Compound Q34) is a potent, specific inhibitor of SARS-CoV-2 cellular entry with IC50 of 15 uM.
Compound Q34 inhibits cellular entry of virus mediated by the SARS-CoV-2 spike protein specifically, but not by the VSV-G glycoprotein.
Compound Q34 inhibits SARS-CoV-2 cellular entry with a broad safety dose range.
Compound Q34 inhibits infection of SARS-CoV-2 pseudovirus in a dose-dependent manner and exhibits no cytotoxicity in a broad dose range.
Compound Q34 inhibits authentic SARS-CoV-2 infection of hACE2-HEK cells.
Compound Q34 inhibits authentic SAR-CoV-2 infection of human iPSC-derived neurons and astrocytes, and human lung cells.
| M.Wt | 354.454 | |
| Formula | C20H26N4O2 | |
| Appearance | Solid | |
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1. Qi Cui, et al. iScience. 2022 Jan 21;25(1):103684.
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