Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-SARS-CoV-2 Related-SARS-CoV-2 Inhibitors-MI-30
MI-30

Chemical Structure : MI-30

CAS No.: 2698348-97-7

Add to Favorites

MI-30 (SARS-CoV-2 Mpro inhibitor MI-30)

Catalog No.: PC-72201Not For Human Use, Lab Use Only.

MI-30 (SARS-CoV-2 Mpro inhibitor MI-30) is a potent, selective SARS-CoV-2 Mpro inhibitor with IC50 of 17.2 nM.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MI-30 (SARS-CoV-2 Mpro inhibitor MI-30) is a potent, selective SARS-CoV-2 Mpro inhibitor with IC50 of 17.2 nM.
    MI-30 dose-dependently protected SARS-CoV-2-infected Vero E6 cells from death with EC50 of 0.54 uM,
    MI-30 inhibited SARS-CoV-2 virus replication in HPAEpiC cells with EC50 of 1.1 nM in RT-qPCR assays.
    MI-30 (20 mg kg–1 day–1, p.o. or i.p.) reduced lung viral loads and lung lesions in a SARS-CoV-2 infection transgenic mouse model.

    Physicochemical Properties

    M.Wt 496.385
    Formula C23H27Cl2N3O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (1S,3aR,6aS)-2-(2-(2,4-dichlorophenoxy)acetyl)-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)octahydrocyclopenta[c]pyrrole-1-carboxamide

    References

    1. Qiao J, et al. Science. 2021 Mar 26;371(6536):1374-1378.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: