| Cat. No. |
Product Name |
Information |
| PC-22709 |
GST-HG171
SARS-CoV-2 3CLPro inhibitor
|
GST-HG171 (Atilotrelvir) is a potent, broad-spectrum, orally bioavailable small-molecule 3C-like (3CL) protease inhibitor, has broad-spectrum activity against different variants of SARS-CoV-2. |
| PC-22611 |
SIMM-036
SARS-CoV-2 PLpro inhibitor
|
SIMM-036 is a specific small molecule SARS-CoV-1 PLpro inhibitor with IC50 of 192.3 nM, inhibits the K63-deubiquitinase activity of SARS-CoV-2 Plpro. |
| PC-22547 |
Virapinib
Macropinocytosis inhibitor
|
Virapinib is a specific inhibitor of macropinocytosis with antiviral activity, limits viral entry by macropinocytosis for several viruses including SARS-CoV-2. |
| PC-22224 |
Mpro61
SARS-CoV-2 Mpro inhibitor
|
Mpro61 is a potent nanomolar inhibitor of SARS-CoV-2 Mpro with IC50 of 44 nM, antiviral EC50 of 80 nM. |
| PC-22071 |
RAY1216
SARS-CoV-2 Mpro inhibitor
|
Leritrelvir (RAY1216) is a potent, selective peptidomimetic inhibitor of SARS-CoV-2 main protease (Mpro) with Ki of 8.4 nM. |
| PC-22009 |
ML2006a4
SARS-CoV-2 Mpro inhibitor
|
ML2006a4 is a highly potent, selective and orally bioavailable SARS-CoV-2 main protease (Mpro) inhibitor with IC50/Ki of 1.05/0.26 nM, shows antiviral EC50 value of 100-120 nM in Huh7.5.1-ACE2-TMPRSS2 cells. |
| PC-21878 |
GC-373
SARS-CoV-2 Mpro inhibitor
|
GC373 is a potent, covalent inhibitor of SARS CoV-2 main protease (MPro) with Kd of 0.15 uM, the reactive aldehyde form of GC376. |
| PC-21803 |
MK-7845
SARS-CoV-2 3CLPro inhibitor
|
MK-7845 is a potent, reversible covalent SARS-CoV-2 3CLPro inhibitor with IC50 of 8.7 nM, inhibits wild-type SARS-CoV-2 3CLPro in SARS-CoV-2 reporter replicon assay in A549 cells with IC50 of 15 nM. |
| PC-21780 |
CMX990
SARS-CoV-2 3CLpro inhibitor
|
CMX990 is a potent, selective and covalent SARS-CoV-2 3CLpro inhibitor with IC50 of 23.4 nM, exhibits good potency (EC50=37 nM) in HeLa-ACE2 SARS-CoV-2 assays. |
| PC-21690 |
MDOLL-0229
SARS-CoV-2 Mac1 inhibitor
|
MDOLL-0229 is a selective small molecule inhibitor for SARS-CoV-2 Mac1 with IC50 of 2.1 uM, inhibits coronavirus replication. |
| PC-21479 |
JC19
SARS-CoV-2 nsp14 degrader
|
JC19 is a a cysteine-reactive small molecule degrader of SARS-CoV-2 nsp14 with DC50 of 8.7 uM in HEK293T cells. |
| PC-21451 |
GC-78-HCl
SARS-CoV-2 Mpro inhibitor
|
GC-78-HCl is a potent nonpeptide SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.19 uM, exhibits excellent antiviral activity (EC50=0.4 uM). |
