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Cat. No. Product Name Information
PC-38259

MM3122

TMPRSS2 inhibitor

MM3122 (MM-3122) is a selective inhibitor of host cell serine protease TMPRSS2 with IC50 of 0.34 nM against recombinant full-length TMPRSS2 protein.
PC-38238

DX600

ACE2 inhibitor

DX600 (DX-600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM.
PC-38237

MU-UNMC-2

Spike RBD-ACE2 inhibitor

MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells.
PC-38236

MU-UNMC-1

Spike RBD-ACE2 inhibitor

MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells.
PC-38235

SB27012

Spike RBD-ACE2 inhibitor

SB27012 (SB 27012) is a small molecule PPI inhibitor of the Spike RBD-ACE2 interaction (IC50=7.7 uM in ELISA assays), binds ACE2 (Kd=210 nM) without affecting ACE2 enzymatic activity.
PC-38178

Ensitrelvir

3CLpro inhibitor

Ensitrelvir (S-217622, S217622) is the first oral, non-covalent, non-peptidic SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate with biochemical IC50 of 13 nM, antiviral EC50 of 0.37 uM.
PC-35231

GC376

3CLpro inhibitor

GC376 (GC-376) is a broad-spectrum antiviral agent that inhibits 3C or 3C-like proteases (3Cpro or 3CLpro) of picornaviruses, noroviruses, and coronaviruses with IC50 of 0.96 (MD145), 0.82 (TGEV) and 0.2 uM (HRV) in FRET protease assays.
PC-24849

KCO237

SARS-CoV-2 Nsp15 inhibitor

KCO237 is a potent, reversible, non-covalent inhibitor of SARS-CoV-2 Nsp15 endoribonuclease with IC50 of 304 nM, inhibits VERO 6 cell infection with SARS-CoV-2.
PC-24841

Dihydrotanshinone I

MERS-CoV inhibitor, MAN1B1 inhibitor

Dihydrotanshinone I (DHT I) is a natural compound extracted from Salvia miltiorrhiza Bunge, exhibits entry-blocking effect for MERS-CoV, also potentially inhibits mannosidase alpha class 1B member 1 (MAN1B1).
PC-24641

ISM3312

Mpro inhibitor

ISM3312 is a potent, irreversible covalent broad-spectrum inhibitor of human coronavirus main protease (Mpro) with IC50 of 14 nM, exhibits potent cellular potency in VeroE6 cell lines with EC50 of 71 nM.
PC-24603

Bafilomycin D

V-ATPase inhibitor, SARS-CoV-2 inhibitor

Bafilomycin D (BafD) is a specific V-ATPase inhibitor and potent nanomolar inhibitor of SARS-CoV-2 Omicron subvariants BA.5 and BA.2.
PC-24591

Ac-Glu-Orn-Arg-kbt

TMPRSS11D inhibitor

PM-5 (Ac-Glu-Orn-Arg-kbt) is a potent, selective TMPRSS2 inhibitor with IC50 of 6.2 nM, exhibits selectivity for TMPRSS2 over TMPRSS11D.

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