| Cat. No. |
Product Name |
Information |
| PC-38259 |
MM3122
TMPRSS2 inhibitor
|
MM3122 (MM-3122) is a selective inhibitor of host cell serine protease TMPRSS2 with IC50 of 0.34 nM against recombinant full-length TMPRSS2 protein. |
| PC-38238 |
DX600
ACE2 inhibitor
|
DX600 (DX-600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM. |
| PC-38237 |
MU-UNMC-2
Spike RBD-ACE2 inhibitor
|
MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells. |
| PC-38236 |
MU-UNMC-1
Spike RBD-ACE2 inhibitor
|
MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells. |
| PC-38235 |
SB27012
Spike RBD-ACE2 inhibitor
|
SB27012 (SB 27012) is a small molecule PPI inhibitor of the Spike RBD-ACE2 interaction (IC50=7.7 uM in ELISA assays), binds ACE2 (Kd=210 nM) without affecting ACE2 enzymatic activity. |
| PC-38178 |
Ensitrelvir
3CLpro inhibitor
|
Ensitrelvir (S-217622, S217622) is the first oral, non-covalent, non-peptidic SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate with biochemical IC50 of 13 nM, antiviral EC50 of 0.37 uM. |
| PC-35231 |
GC376
3CLpro inhibitor
|
GC376 (GC-376) is a broad-spectrum antiviral agent that inhibits 3C or 3C-like proteases (3Cpro or 3CLpro) of picornaviruses, noroviruses, and coronaviruses with IC50 of 0.96 (MD145), 0.82 (TGEV) and 0.2 uM (HRV) in FRET protease assays. |
| PC-24849 |
KCO237
SARS-CoV-2 Nsp15 inhibitor
|
KCO237 is a potent, reversible, non-covalent inhibitor of SARS-CoV-2 Nsp15 endoribonuclease with IC50 of 304 nM, inhibits VERO 6 cell infection with SARS-CoV-2. |
| PC-24841 |
Dihydrotanshinone I
MERS-CoV inhibitor, MAN1B1 inhibitor
|
Dihydrotanshinone I (DHT I) is a natural compound extracted from Salvia miltiorrhiza Bunge, exhibits entry-blocking effect for MERS-CoV, also potentially inhibits mannosidase alpha class 1B member 1 (MAN1B1). |
| PC-24641 |
ISM3312
Mpro inhibitor
|
ISM3312 is a potent, irreversible covalent broad-spectrum inhibitor of human coronavirus main protease (Mpro) with IC50 of 14 nM, exhibits potent cellular potency in VeroE6 cell lines with EC50 of 71 nM. |
| PC-24603 |
Bafilomycin D
V-ATPase inhibitor, SARS-CoV-2 inhibitor
|
Bafilomycin D (BafD) is a specific V-ATPase inhibitor and potent nanomolar inhibitor of SARS-CoV-2 Omicron subvariants BA.5 and BA.2. |
| PC-24591 |
Ac-Glu-Orn-Arg-kbt
TMPRSS11D inhibitor
|
PM-5 (Ac-Glu-Orn-Arg-kbt) is a potent, selective TMPRSS2 inhibitor with IC50 of 6.2 nM, exhibits selectivity for TMPRSS2 over TMPRSS11D. |
