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3CLpro covalent inhibitor 14c

Chemical Structure : 3CLpro covalent inhibitor 14c

CAS No.: 2757970-20-8

3CLpro covalent inhibitor 14c

Catalog No.: PC-72193Not For Human Use, Lab Use Only.

3CLpro covalent inhibitor 14c is a potent, covalent inhibitor of SARS-CoV-2 3CL pro with IC50 of 170 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    3CLpro covalent inhibitor 14c is a potent, covalent inhibitor of SARS-CoV-2 3CLpro with IC50 of 170 nM.

    Physicochemical Properties

    M.Wt 512.065
    Formula C27H30ClN3O3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(N-(4-(tert-butyl)phenyl)vinylsulfonamido)-N-(3-chlorophenethyl)-2-(pyridin-3-yl)acetamide

    References

    1. Julia K Stille, et al. Eur J Med Chem. 2022 Feb 5;229:114046.

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