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Chemical Structure : SARS PLpro inhibitor rac5c
Catalog No.: PC-72190Not For Human Use, Lab Use Only.
SARS PLpro inhibitor rac5c is a potent, small molecule inhibitor of SARS PLpro with IC50 of 0.81 uM.
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SARS PLpro inhibitor rac5c is a potent, small molecule inhibitor of SARS PLpro with IC50 of 0.81 uM.
Nsp3 expression decreased Lys48‐linked polyubiquitin, which was inhibited by rac5c in a dose‐dependent manner.
rac5c (33 uM) reduced SARS‐CoV‐2‐induced CPE.
| M.Wt | 403.526 | |
| Formula | C25H29N3O2 | |
| Appearance | Solid | |
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1. Theresa Klemm, et al. EMBO J. 2020 Sep 15;39(18):e106275.
2. Yahira M Báez-Santos, et al. J Med Chem. 2014 Mar 27;57(6):2393-412.
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