SARS PLpro inhibitor rac5c

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Chemical Structure : SARS PLpro inhibitor rac5c

Catalog No.: PC-72190Not For Human Use, Lab Use Only.

SARS PLpro inhibitor rac5c is a potent, small molecule inhibitor of SARS PLpro with IC50 of 0.81 uM.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SARS PLpro inhibitor rac5c is a potent, small molecule inhibitor of SARS PLpro with IC50 of 0.81 uM.
Nsp3 expression decreased Lys48‐linked polyubiquitin, which was inhibited by rac5c in a dose‐dependent manner.
rac5c (33 uM) reduced SARS‐CoV‐2‐induced CPE.

Physicochemical Properties

M.Wt	403.526
Formula	C25H29N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((2-methoxypyridin-4-yl)methyl)-1-(1-(naphthalen-1-yl)ethyl)piperidine-4-carboxamide

References

1. Theresa Klemm, et al. EMBO J. 2020 Sep 15;39(18):e106275.

2. Yahira M Báez-Santos, et al. J Med Chem. 2014 Mar 27;57(6):2393-412.

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