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Chemical Structure : MU-UNMC-1
Catalog No.: PC-38236Not For Human Use, Lab Use Only.
MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells.
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MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells.
MU-UNMC-1 blocked the entry of pseudovirus particles expressing SARS-CoV-2 Spike glycoprotein.
MU-UNMC-1 effectively blocked the replication of rapidly transmitting variants of concern: South African variant B.1.351 Omicron (IC50=9.27 μM) and Scotland variant B.1.222 (IC50=2.64 μM).
| M.Wt | 366.362 | |
| Formula | C14H10N2O6S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Arpan Acharya, et al. J Virol. 2021 Nov 23;95(24):e0143721.
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