| Cat. No. |
Product Name |
Information |
| PC-72069 |
EIDD-1931
SARS-CoV-2 inhibitor
|
EIDD-1931 (Beta-d-N4-hydroxycytidine, β-d-N4-hydroxycytidine, NHC) is an active metabolite of EIDD-2801 with broad-spectrum antiviral inhibitor of SARS-CoV-2. |
| PC-38282 |
P2165
Spike RBD-ACE2 inhibitor
|
P2165 (P-2165) is a anticoronaviruse chemical probe that inhibit SARS-CoV-2 Spike binding to human ACE2 receptor. |
| PC-38281 |
P2119
Spike RBD-ACE2 inhibitor
|
P2119 (P-2119) is an anticoronaviruse chemical probe that inhibit SARS-CoV-2 Spike binding to human ACE2 receptor. |
| PC-38259 |
MM3122
TMPRSS2 inhibitor
|
MM3122 (MM-3122) is a selective inhibitor of host cell serine protease TMPRSS2 with IC50 of 0.34 nM against recombinant full-length TMPRSS2 protein. |
| PC-38238 |
DX600
ACE2 inhibitor
|
DX600 (DX-600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM. |
| PC-38237 |
MU-UNMC-2
Spike RBD-ACE2 inhibitor
|
MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells. |
| PC-38236 |
MU-UNMC-1
Spike RBD-ACE2 inhibitor
|
MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells. |
| PC-38235 |
SB27012
Spike RBD-ACE2 inhibitor
|
SB27012 (SB 27012) is a small molecule PPI inhibitor of the Spike RBD-ACE2 interaction (IC50=7.7 uM in ELISA assays), binds ACE2 (Kd=210 nM) without affecting ACE2 enzymatic activity. |
| PC-38178 |
S-217622
3CLpro inhibitor
|
S-217622 (Ensitrelvir, S217622) is the first oral, non-covalent, non-peptidic SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate with biochemical IC50 of 13 nM, antiviral EC50 of 0.37 uM. |
| PC-23632 |
TDI-015051
SARS-CoV-2 NSP14 inhibitor
|
TDI-015051 is a highly potent, specific inhibitor of SARS-CoV-2 NSP14 RNA cap methyltransferase with Kd of 61 pM and IC50 of <0.15 nM, inhibits viral mRNA translation. |
| PC-23595 |
SARS-CoV-2 nsp12 NiRAN domain inhibitor NCI-2
nsp12 NiRAN domain inhibitor
|
NCI-2 is a small molecule inhibitor of SARS-CoV-2 nsp12 NiRAN domain, covalently binds to an active site cysteine (Cys53) in the NiRAN domain, inhibiting nsp12-dependent AMPylation of nsp9 with IC50 of 4.3 uM. |
| PC-23545 |
GZNL-P36
SARS-CoV-2 PLpro inhibitor
|
GZNL-P36 is a potent, selective and orally bioavailable SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 6.45 nM, ITC Kd value of 24.6 nM. |
