| Cat. No. |
Product Name |
Information |
| PC-38238 |
DX600
ACE2 inhibitor
|
DX600 (DX-600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM. |
| PC-38237 |
MU-UNMC-2
Spike RBD-ACE2 inhibitor
|
MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells. |
| PC-38236 |
MU-UNMC-1
Spike RBD-ACE2 inhibitor
|
MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells. |
| PC-38235 |
SB27012
Spike RBD-ACE2 inhibitor
|
SB27012 (SB 27012) is a small molecule PPI inhibitor of the Spike RBD-ACE2 interaction (IC50=7.7 uM in ELISA assays), binds ACE2 (Kd=210 nM) without affecting ACE2 enzymatic activity. |
| PC-38178 |
S-217622
3CLpro inhibitor
|
S-217622 (Ensitrelvir, S217622) is the first oral, non-covalent, non-peptidic SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate with biochemical IC50 of 13 nM, antiviral EC50 of 0.37 uM. |
| PC-23384 |
Jun12682
SARS-CoV-2 PLpro inhibitor
|
Jun12682 is a potent SARS-CoV-2 papain-like protease (PLpro) inhibitor with Ki/IC50 values of 37.7/106.8 nM. |
| PC-23375 |
NZ-804
SARS-CoV-2 Mpro inhibitor
|
NZ-804 is a potent, selective, non-peptidic, non-covalent inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 9 nM and antiviral EC50 of 14 nM. |
| PC-23359 |
ATV014
SARS-CoV-2 RdRp inhibitor
|
ATV014 (SHEN26) is a potent, orally active anti-SARS-CoV-2 nucleoside compound with EC50 of 0.48 uM against SARS-CoV-2 replicon, inhibits SARS-CoV-2 RdRp. |
| PC-23213 |
TL1228
GRP78 inhibitor
|
TL1228 is a small molecule inhibitor of SARS-CoV-2 and its target cells, blocking the recognition of the GRP78 cellular receptor by the viral Spike protein, also is a selective inhibitor of the dihydrofolate reductase (DHFR) type B1. |
| PC-22984 |
PF-07957472
SARS-CoV-2 PLpro inhibitor
|
PF-07957472 is a potent, selective, and orally available SARS-CoV-2 papain-like protease (PLpro) inhibitor with Ki of 2 nM, exhibits cell antiviral potency in Vero E6 cells with EC50 of 147 nM. |
| PC-22983 |
P23E02
Nsp1-SL1 inhibitor
|
P23E02 is a small molecule inhibitor of SARS-CoV-2 viral protein Nsp1-40S ribosomal subunit (stem-loop 1, SL1) interaction with IC50 of 2.26 uM, exhibits antiviral efficacy against various sarbecoviruses. |
| PC-22947 |
AVI-4206
SARS-CoV-2 Mac1 inhibitor
|
AVI-4206 is a potent, specific small molecule inhibitor of SARS-CoV-2 ADP-ribosylhydrolase macrodomain (Mac1) with IC50 of 20 nM in HTRF assays. |
