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SARS 3CLpro inhibitor 17a

Chemical Structure : SARS 3CLpro inhibitor 17a

CAS No.: 1473419-56-5

SARS 3CLpro inhibitor 17a

Catalog No.: PC-72199Not For Human Use, Lab Use Only.

SARS 3CLpro inhibitor 17a is a potent, selective, noncovalent inhibitor of the SARS-CoV 3CL protease (3CLpro) with IC50 of 53 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SARS 3CLpro inhibitor 17a is a potent, selective, noncovalent inhibitor of the SARS-CoV 3CL protease (3CLpro) with IC50 of 53 nM.

    Physicochemical Properties

    M.Wt 424.522
    Formula C25H20N4OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-([1,1'-biphenyl]-4-yl)-2-(1H-benzo[d][1,2,3]triazol-1-yl)-N-(thiophen-3-ylmethyl)acetamide

    References

    1. Han SH, et al. J Med Chem. 2021 Aug 4:acs.jmedchem.1c00598.

    2. Turlington M, et al. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6172-7.

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