| Cat. No. |
Product Name |
Information |
| PC-21690 |
MDOLL-0229
SARS-CoV-2 Mac1 inhibitor
|
MDOLL-0229 is a selective small molecule inhibitor for SARS-CoV-2 Mac1 with IC50 of 2.1 uM, inhibits coronavirus replication. |
| PC-21479 |
JC19
SARS-CoV-2 nsp14 degrader
|
JC19 is a a cysteine-reactive small molecule degrader of SARS-CoV-2 nsp14 with DC50 of 8.7 uM in HEK293T cells. |
| PC-21451 |
GC-78-HCl
SARS-CoV-2 Mpro inhibitor
|
GC-78-HCl is a potent nonpeptide SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.19 uM, exhibits excellent antiviral activity (EC50=0.4 uM). |
| PC-21419 |
Compound 212-148
TMPRSS2 inhibitor
|
Compound 212-148 a bispecific, dual inhibitor of both TMPRSS2 and cysteine proteases cathepsin L/B (CTSL/CTSB) with IC50 of 1.38 uM and 2.13/64.07 nM, respectively, demonstrates antiviral activity against various SARS-CoV-2 variants. |
| PC-21119 |
D-4-77
SARS-CoV-2 Mpro inhibitor
|
D-4-77 is a potent, covalent peptidyl inhibitor of SARS-CoV-2 main protease (Mpro) with IC50 of 0.95 uM and antiviral EC50 of 0.49 uM. |
| PC-20951 |
NACE2i
ACE2 inhibitor
|
NACE2i is a cell permeable, specific and selective peptide inhibitor of nuclear ACE2, inhibits binding between IMP1α and ACE2 and SARS-CoV-2 viral replication. |
| PC-20900 |
PAV-104
SARS-CoV-2 assembly inhibitor
|
PAV-104 (PAV104) is a novel viral assembly inhibitor, shows potent anti-SARS-CoV-2 activity in Calu-3 cells with EC50 of 1.7 nM and EC90 of 23.5 nM, inhibits the oligomerization of the SARS-CoV-2 nucleocapsid. |
| PC-38708 |
ALG-097111
SARS-CoV-2 3CLpro inhibitor
|
ALG-097111 is a potent and selective SARS-CoV-2 3-chymotrypsin-like cysteine protease (3CLpro) with IC50 of 7 nM, without effect against human cathepsin L (IC50>10 uM). |
| PC-72810 |
SGC-CK2-1N
CSNK2 inhibitor
|
SGC-CK2-1N is the negative control of SGC-CK2-1. |
| PC-72747 |
Titanocene dichloride
Spike-ACE2 inhibitor
|
Titanocene dichloride (Cp2 TiCl 2) is an active inhibitor of interaction between SARS-CoV-2 spike (S) protein with the ACE2 receptor (IC50=3.9 uM) |
| PC-72681 |
SARS-CoV-2 nsp5 inhibitor 39
SARS-CoV-2 nsp5 inhibitor
|
SARS-CoV-2 nsp5 inhibitor 39 is a small molecule SARS-CoV-2 nsp5 inhibitor , inhibits SARS-CoV-2 replication with IC50 of 4.7 uM in multicycle replication assays. |
| PC-72491 |
SCoV2 Plpro-Probe-7
SCoV2 Plpro substrate
|
SCoV2 Plpro-Probe-7 is a peptidomimetic activity probe and substrate for SCoV2 PLpro, exhibits excellent sensitivity to wild-type (WT) SCoV2 PLpro, but not to the catalytically inactive mutant, SCoV2 PLproC112S, consists of a fluorogenic HCC conjugated to PLpro's N terminus, and DABCYL to its C-terminal lysine. |
