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XR8-24

Chemical Structure : XR8-24

CAS No.: 2817810-97-0

XR8-24

Catalog No.: PC-26443Not For Human Use, Lab Use Only.

XR8-24 is a potent, selective SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 0.56 uM and binding KD of 0.37 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

XR8-24 is a potent, selective SARS-CoV-2 papain-like protease (PLpro) inhibitor with IC50 of 0.56 uM and binding KD of 0.37 uM.

Physicochemical Properties

M.Wt 474.67
Formula C28H34N4OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-5-(azetidin-3-ylamino)-2-methyl-N-(1-(3-(5-(pyrrolidin-1-ylmethyl)thiophen-2-yl)phenyl)ethyl)benzamide

References

1. Zhengnan Shen, et al. J Med Chem. 2022 Feb 24;65(4):2940-2955.

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