| Cat. No. |
Product Name |
Information |
| PC-22802 |
EDP-235
3CLpro inhibitor
|
EDP-235 (Zevotrelvir, EDP235) is a potent, selective inhibitor of SARS-CoV-2 3CLpro with IC50 of 4.0 nM, Kiapp of 3.0 nM, reversibly binds and inhibits the 3CLpro. |
| PC-22258 |
PF-07817883
SARS-CoV-2 Mpro inhibitor
|
PF-07817883 (Ibuzatrelvir) is a second-generation, orally bioavailable, SARS-CoV-2 main protease (Mpro) with Ki value of 2.48 nM, EC50 of 180 nM for inhibition of SARS-CoV-2 induced cytopathic effect (CPE). |
| PC-22071 |
RAY1216
SARS-CoV-2 Mpro inhibitor
|
Leritrelvir (RAY1216) is a potent, selective peptidomimetic inhibitor of SARS-CoV-2 main protease (Mpro) with Ki of 8.4 nM. |
| PC-21780 |
CMX990
SARS-CoV-2 3CLpro inhibitor
|
CMX990 is a potent, selective and covalent SARS-CoV-2 3CLpro inhibitor with IC50 of 23.4 nM, exhibits good potency (EC50=37 nM) in HeLa-ACE2 SARS-CoV-2 assays. |
| PC-21710 |
AC1115
SARS-CoV-2 Mpro inhibitor
|
AC1115 is a potent, selective, next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, AC1115 is the active form of Olgotrelvir. |
| PC-21709 |
Olgotrelvir
SARS-CoV-2 Mpro inhibitor
|
Olgotrelvir (STI-1558) is a next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, Olgotrelvir is the prodrug of AC1115. |
| PC-21450 |
FB2001
SARS-CoV-2 Mpro inhibitor
|
Bofutrelvir (FB2001) is a potent, selective and covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 value of 53 nM. |
| PC-21335 |
MAT-POS-e194df51-1
SARS-CoV-2 Mpro inhibitor
|
MAT-POS-e194df51-1 is potent, selective and noncovalent SARS-CoV-2 main protease (SARS-CoV-2 Mpro) inhibitor with IC50 of 36.8 nM, shows antiviral activity with EC50 of 64 nM in A549-ACE2-TMPRSS2 cells. |
| PC-21248 |
Pomotrelvir
SARS-CoV-2 Mpro inhibitor
|
Pomotrelvir (PBI-0451) is a potent competitive inhibitor of SARS-CoV-2 Mpro (Ki=2.7 nM) with high selectivity against human proteases, inhibits wild-type SARS-CoV-2 Mpro with IC50 of 24 nM. |
| PC-21243 |
Simnotrelvir
SARS-CoV-2 3CLpro inhibitor
|
Simnotrelvir (SSD8432, SIM0417) is a potent, selective, covalent and orally bioavailable SARS-CoV-2 3C-like protease (3CLpro) inhibitor with IC50 of 9 nM in enzymatic inhibition assays. |
| PC-21077 |
GS-441524
Viral RdRp inhibitor
|
GS-441524 (GS441524) is the active metabolite of Remdesivir, inhibits viral RNA dependent RNA polymerase (RdRp) from the Flaviviridae family. |
| PC-21075 |
GS-5245
Antiviral
|
GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo. |
