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Cat. No. Product Name Information
PC-21709

Olgotrelvir

SARS-CoV-2 Mpro inhibitor

Olgotrelvir (STI-1558) is a next-generation antiviral targeting SARS-CoV-2 Mpro and host lysosomal cysteine protease cathepsin L (CTSL) with high antiviral activity, Olgotrelvir is the prodrug of AC1115.
PC-21077

GS-441524

Viral RdRp inhibitor

GS-441524 (GS441524) is the active metabolite of Remdesivir, inhibits viral RNA dependent RNA polymerase (RdRp) from the Flaviviridae family.
PC-21075

GS-5245

Antiviral

GS-5245 (Obeldesivir) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo.
PC-49865

TKB248

SARS-CoV-2 Mpro inhibitor

TKB248 (TKB-248) is a potent, specific SARS-CoV-2 Mpro inhibitor with IC50 of 74 nM, exhibits highly potent anti-SARS-CoV-2 activity with EC50 and EC95 values of 0.22 and 0.87 µM, respectively.
PC-49864

TKB245

SARS-CoV-2 Mpro inhibitor

TKB245 (TKB-245) is a potent, specific SARS-CoV-2 Mpro inhibitor with IC50 of 7 nM, exhibits highly potent anti-SARS-CoV-2 activity with EC50 and EC95 values of 0.03 and 0.53 µM, respectively.
PC-49191

SARS-CoV-2 PLpro inhibitor 7

PLpro inhibitor

SARS-CoV-2 PLpro inhibitor 7 is a potent, selective and covalent inhibitor of SARS-CoV-2 papain-like protease (PLpro) with IC50 of 94 nM, shows SARS-CoV-2 antiviral activity with EC50 of 1.1 uM.
PC-49155

FOY-251

TMPRSS2 inhibitor

FOY-251 is a camostat metabolite and inhibitor of TMPRSS2 protease activity with IC50 of 33.3 nM, completely suppresses TMPRSS2 activity at 1 uM, inhibit SARS-2-S-driven cell entry with comparable efficiency (EC50=178 nM) with camostat mesylate.
PC-49140

JMX0286

SARS-CoV-2 3CLPro inhibitor

JMX0286 is a potent, specific and allosteric inhibitor against SARS-CoV-2 3CLpro with IC50 of 4.8 uM in FRET based screening assays, shows strong inhibition of SARS-CoV-2 virus with EC50 of 2.25 uM in A549-hACE2 cells.
PC-49052

Z8539_0072

SARS-CoV-2 Nsp3 inhibitor

Z8539_0072 is a potent SARS-CoV-2 macrodomain inhibitor that binds to the NSP3 macrodomain of SARS-CoV-2 (Mac1) with IC50 of 460 nM.
PC-47067

RI173

SARS-CoV-2 inhibitor

RI173 is a potent, covalent, triple-acting inhibitor of SARS-CoV-2 protease Mpro, PLpro and human cathepsin L with IC50 of 0.6 uM, 0.2 uM and 1.7 uM, respectively.
PC-38735

VV116

SARS-CoV-2 inhibitor

VV116 (Mindeudesivir, JT001) is a promising orally active remdesivir derivative against SARS-CoV-2, targeting the viral RNA-dependent RNA polymerase through its nucleoside triphosphate form with IC50 of 0.67 uM.
PC-38498

SARS-CoV-2 nsp14 inhibitor 25

SARS-CoV-2 nsp14 inhibitor

SARS-CoV-2 nsp14 inhibitor 25 is a highly potent, selective, nucleoside-derived inhibitor of SARS-CoV-2 nsp14 (N7-guanine)-methyltransferase (N7-MTase) with IC50 of 19 nM, no inhibition against human RNA N7-MTase (hRNMT, IC50>50 uM).

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