| Cat. No. |
Product Name |
Information |
| PC-73344 |
Pin1 inhibitor H-77
Pin1 inhibitor
|
Pin1 inhibitor H-77 (H-77) is a small molecule Pin1 inhibitor that blocks SARS-CoV-2 proliferation with EC50 of 3.2 uM. |
| PC-73341 |
Coronastat
SARS-CoV-2 3CLpro inhibitor
|
Coranastat (NK01-63) is a GC376 analog with improved potency, and highly potent, selective SARS-CoV-2 3CL protease inhibitor with IC50 of 16 nM, exhibits antiviral potency with EC50 of 6 nM in Huh-7ACE2 cellular assays. |
| PC-73340 |
MAC-5576
SARS-CoV-2 3CLpro inhibitor
|
MAC-5576 (MAC5576) is a small molecule, covalent inhibitor of coronavirus SARS-CoV 3CLpro with IC50 of 0.5 uM, inhibits SARS-CoV-2 3CL protease with IC50 of 0.093 uM. |
| PC-73233 |
SSAA09E2
Spike-ACE2 inhibitor
|
SSAA09E2 is a small molecule inhibitor of SARS entry, blocks early interactions of SARS-CoV surface glycoprotein S (SARS-S) with angiotensin converting enzyme 2 (ACE2), also inhibits SARS-CoV-2 Spike-ACE2 interaction. |
| PC-73166 |
Molnupiravir N-1
Molnupiravir Impurity
|
Molnupiravir N-1 is an impurity chemical of Molnupiravir (EIDD-2801, MK4482), which is anti-SARS-CoV-2 for treatment of COVID-19. |
| PC-73013 |
Z222979552
SARS-CoV-2 Mpro inhibitor
|
Z222979552 is a small molecule non-covalent SARS-CoV-2 Mpro inhibitor with IC50 of 1.0 uM. |
| PC-72893 |
(S)-chlorcyclizine
SARS CoV fusion inhibitor
|
(S)-chlorcyclizine ((S)-CCZ) is an approved antihistamine drug that is related to dichlorcyclizine (DCCZ), inhibits SARS-CoV and SARS-CoV-2 S-mediated infection in MA104 cells with EC50 of 6.91 and 4.09 uM. |
| PC-72889 |
NBCoV2
CoV fusion inhibitor
|
NBCoV2 is a highly potent small molecule viral fusion inhibitor with potential pan-Coronavirus activity (SARS-CoV IC50=13.8 nM, SARS-CoV-2 IC50=22.8 nM, MERS-CoV IC50=77 nM, cell-based single-cycle assays). |
| PC-72888 |
NBCoV1
Viral fusion inhibitor
|
NBCoV1 is a highly potent small molecule viral fusion inhibitor with potential pan-Coronavirus activity (SARS-CoV IC50=17 nM, SARS-CoV-2 IC50=51 nM, MERS-CoV IC50=75 nM, cell-based single-cycle assays). |
| PC-72814 |
Acriflavine
PLpro inhibitor
|
Acriflavine (Acriflavin) is a topical antiseptic that found to be a potent papain-like protease (PLpro) inhibitor, inhibits SARS-CoV-2 and other betacoronaviruses. |
| PC-72808 |
CSNK2A inhibitor 2
CSNK2 inhibitor
|
CSNK2A inhibitor 2 (CK2 inhibitor Compound 2) is a potent, selective, cell active ATP-competitive inhibitor of host protein kinase Casein Kinase 2 (CSNK2A1/2, pIC50=8.5-8.6), inhibits the pathogenic β-coronaviruses including SARS-CoV-2 (MHV pIC50=8.6) |
| PC-72806 |
DS0464
SARS-CoV-2 nsp14 inhibitor
|
DS0464 is a selective, bisubstrate competitive inhibitor SARS-CoV-2 nonstructural protein 14 (nsp14) with IC50 of 1.1 uM, also selective against 28 out of 33 RNA, DNA, and protein MTases. |
