| Cat. No. |
Product Name |
Information |
| PC-38259 |
MM3122
TMPRSS2 inhibitor
|
MM3122 (MM-3122) is a selective inhibitor of host cell serine protease TMPRSS2 with IC50 of 0.34 nM against recombinant full-length TMPRSS2 protein. |
| PC-38238 |
DX-600
ACE2 inhibitor
|
DX-600 (DX600) is a potent, specific peptide inhibitor of Angiotensin-converting enzyme 2 (ACE2) with Ki of 2.8 nM. |
| PC-38237 |
MU-UNMC-2
|
MU-UNMC-2 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 1.72 uM in human bronchial epithelial cells. |
| PC-38236 |
MU-UNMC-1
Spike RBD-ACE2 inhibitor
|
MU-UNMC-1 is a potential small-molecule inhibitor of S-RBD and ACE-2 interaction, shows antiviral activity against SARS-CoV-2 with IC50 of 0.67 uM in human bronchial epithelial cells. |
| PC-38235 |
SB27012
Spike RBD-ACE2 inhibitor
|
SB27012 (SB 27012) is a small molecule PPI inhibitor of the Spike RBD-ACE2 interaction (IC50=7.7 uM in ELISA assays), binds ACE2 (Kd=210 nM) without affecting ACE2 enzymatic activity. |
| PC-38178 |
S-217622
3CLpro inhibitor
|
S-217622 (Ensitrelvir, S217622) is the first oral, non-covalent, non-peptidic SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate with biochemical IC50 of 13 nM, antiviral EC50 of 0.37 uM. |
| PC-22258 |
PF-07817883
SARS-CoV-2 Mpro inhibitor
|
PF-07817883 (Ibuzatrelvir) is a second-generation, orally bioavailable, SARS-CoV-2 main protease (Mpro) with Ki value of 2.48 nM, EC50 of 180 nM for inhibition of SARS-CoV-2 induced cytopathic effect (CPE). |
| PC-22224 |
Mpro61
SARS-CoV-2 Mpro inhibitor
|
Mpro61 is a potent nanomolar inhibitor of SARS-CoV-2 Mpro with IC50 of 44 nM, antiviral EC50 of 80 nM. |
| PC-22071 |
RAY1216
SARS-CoV-2 Mpro inhibitor
|
Leritrelvir (RAY1216) is a potent, selective peptidomimetic inhibitor of SARS-CoV-2 main protease (Mpro) with Ki of 8.4 nM. |
| PC-22009 |
ML2006a4
SARS-CoV-2 Mpro inhibitor
|
ML2006a4 is a highly potent, selective and orally bioavailable SARS-CoV-2 main protease (Mpro) inhibitor with IC50/Ki of 1.05/0.26 nM, shows antiviral EC50 value of 100-120 nM in Huh7.5.1-ACE2-TMPRSS2 cells. |
| PC-21878 |
GC-373
SARS-CoV-2 Mpro inhibitor
|
GC373 is a potent, covalent inhibitor of SARS CoV-2 main protease (MPro) with Kd of 0.15 uM, the reactive aldehyde form of GC376. |
| PC-21803 |
MK-7845
SARS-CoV-2 3CLPro inhibitor
|
MK-7845 is a potent, reversible covalent SARS-CoV-2 3CLPro inhibitor with IC50 of 8.7 nM, inhibits wild-type SARS-CoV-2 3CLPro in SARS-CoV-2 reporter replicon assay in A549 cells with IC50 of 15 nM. |
