Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-SARS-CoV-2 Related-SARS-CoV-2 Inhibitors-MAC-5576
MAC-5576

Chemical Structure : MAC-5576

CAS No.: 219929-01-8

Add to Favorites

MAC-5576 (MAC5576, MAC-0005576)

Catalog No.: PC-73340Not For Human Use, Lab Use Only.

MAC-5576 (MAC5576) is a small molecule, covalent inhibitor of coronavirus SARS-CoV 3CLpro with IC50 of 0.5 uM, inhibits SARS-CoV-2 3CL protease with IC50 of 0.093 uM.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MAC-5576 (MAC5576) is a small molecule, covalent inhibitor of coronavirus SARS-CoV 3CLpro with IC50 of 0.5 uM, inhibits SARS-CoV-2 3CL protease with IC50 of 0.093 uM.
    MAC-5576 inhibits Hepatitis A virus (HAV) 3Cpro with IC50 of 0.54 uM.
    MAC-5576 selectively binds to the active site cysteine 145 of the SARS-CoV-2 3CL protease.

    Physicochemical Properties

    M.Wt 239.673
    Formula C10H6ClNO2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-chloropyridin-3-yl thiophene-2-carboxylate

    References

    1. Jan E Blanchard, et al. Chem Biol. 2004 Oct;11(10):1445-53.

    2. Hengrui Liu, et al. Nat Commun. 2022 Apr 7;13(1):1891.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: