KCO237 | SARS-CoV-2 Nsp15 inhibitor | Probechem Biochemicals

Chemical Structure : KCO237

KCO237 (KCO-237)

Catalog No.: PC-24849Not For Human Use, Lab Use Only.

KCO237 is a potent, reversible, non-covalent inhibitor of SARS-CoV-2 Nsp15 endoribonuclease with IC50 of 304 nM, inhibits VERO 6 cell infection with SARS-CoV-2.

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Biological Activity

KCO237 is a potent, reversible, non-covalent inhibitor of SARS-CoV-2 Nsp15 endoribonuclease with IC50 of 304 nM, inhibits VERO 6 cell infection with SARS-CoV-2.

Physicochemical Properties

M.Wt	298.38
Formula	C15H10N2OS2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-5-((E)-3-(quinolin-4-yl)allylidene)-2-thioxothiazolidin-4-one

References

1. Nimer Mehyar, et al. J Biol Chem. 2025 Jun 23:110409.

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KCO237 (KCO-237)

Biological Activity

Physicochemical Properties

References

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