EGT710 | SARS-CoV-2 Mpro inhibitor | Probechem Biochemicals

Chemical Structure : EGT710

EGT710 (NVP-EGT710, EGT-710)

Catalog No.: PC-26050Not For Human Use, Lab Use Only.

EGT710 (NVP-EGT710) is a potent, selective and oral nonpeptidomimetic reversible covalent SARS-CoV-2 Mpro inhibitor with IC50 of 7 nM, shows cellular potency with IC50 of 11 nM in CPE assay in Vero E6 cells.

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Biological Activity

Physicochemical Properties

M.Wt	383.33
Formula	C19H12F3N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-3-(Isoquinolin-4-yl)-2-oxo-1-(6-(trifluoromethyl)pyridin-3-yl)imidazolidine-4-carbonitrile

References

1. Papillon JPN, et al. J Med Chem. 2026 Feb 9. doi: 10.1021/acs.jmedchem.5c02360.

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EGT710 (NVP-EGT710, EGT-710)

Biological Activity

Physicochemical Properties

References

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