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Chemical Structure : MI-09
Catalog No.: PC-72200Not For Human Use, Lab Use Only.
MI-09 (SARS-CoV-2 Mpro inhibitor MI-09) is a potent, selective SARS-CoV-2 Mpro inhibitor with IC50 of 15.2 nM.
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MI-09 (SARS-CoV-2 Mpro inhibitor MI-09) is a potent, selective SARS-CoV-2 Mpro inhibitor with IC50 of 15.2 nM.
MI-09 dose-dependently protected SARS-CoV-2-infected Vero E6 cells from death with EC50 of 0.86 uM.
MI-09 inhibited SARS-CoV-2 virus replication in HPAEpiC cells with EC50 of 1.2 nM in RT-qPCR assays.
MI-09 (20 mg kg–1 day–1, p.o. or i.p.) reduced lung viral loads and lung lesions in a SARS-CoV-2 infection transgenic mouse model.
| M.Wt | 511.498 | |
| Formula | C24H28F3N3O6 | |
| Appearance | Solid | |
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1. Qiao J, et al. Science. 2021 Mar 26;371(6536):1374-1378.
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