Jun9-88-6R

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Chemical Structure : Jun9-88-6R

Catalog No.: PC-72517Not For Human Use, Lab Use Only.

Jun9-88-6R is a potent, selective, covalent SARS-CoV-2 Mpro inhibitor with IC50 of 0.08 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Jun9-88-6R is a potent, selective, covalent SARS-CoV-2 Mpro inhibitor with IC50 of 0.08 uM.
Jun9-88-6R is highly selective toward Mpro and does not inhibit the host calpain I, cathepsins B, K, L, caspase-3, and trypsin.
Jun9-88-6R inhibited SARS-CoV-2 replication in Vero E6 cells with IC50 of 0.58 uM.

Physicochemical Properties

M.Wt	686.242
Formula	C29H24Br3N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-([1,1'-biphenyl]-4-yl)-2,2,2-tribromo-N-((R)-2-oxo-2-(((S)-1-phenylethyl)amino)-1-(pyridin-3-yl)ethyl)acetamide

References

1. Chunlong Ma, et al. J Am Chem Soc. 2021 Dec 15;143(49):20697-20709.

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Jun9-88-6R

Biological Activity

Physicochemical Properties

References

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