Jun9-57-3R

Chemical Structure : Jun9-57-3R

Catalog No.: PC-72518Not For Human Use, Lab Use Only.

Jun9-57-3R is a potent, selective, covalent SARS-CoV-2 Mpro inhibitor with IC50 of 0.05 uM.

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Biological Activity

Jun9-57-3R is a potent, selective, covalent SARS-CoV-2 Mpro inhibitor with IC50 of 0.05 uM.
Jun9-57-3R forms a covalent adduct with the catalytic cysteine Cys145 of SARS-CoV-2 Mpro.

Physicochemical Properties

M.Wt	472.973
Formula	C27H25ClN4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(1H-pyrrol-1-yl)phenyl)-2-chloro-N-((R)-2-oxo-2-(((S)-1-phenylethyl)amino)-1-(pyridin-3-yl)ethyl)acetamide

References

1. Chunlong Ma, et al. J Am Chem Soc. 2021 Dec 15;143(49):20697-20709.

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Jun9-57-3R

Biological Activity

Physicochemical Properties

References

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