Catalog No.: PC-49155Not For Human Use, Lab Use Only.
FOY-251 is a camostat metabolite and inhibitor of TMPRSS2 protease activity with IC50 of 33.3 nM, completely suppresses TMPRSS2 activity at 1 uM, inhibit SARS-2-S-driven cell entry with comparable efficiency (EC50=178 nM) with camostat mesylate.
FOY-251 is a camostat metabolite and inhibitor of TMPRSS2 protease activity with IC50 of 33.3 nM, completely suppresses TMPRSS2 activity at 1 uM, inhibit SARS-2-S-driven cell entry with comparable efficiency (EC50=178 nM) with camostat mesylate.
Physicochemical Properties
M.Wt
409.413
Formula
C17H19N3O7S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(4-((4-guanidinobenzoyl)oxy)phenyl)acetic acid compound with methanesulfonic acid (1:1)
References
1. Shrimp JH, et al. bioRxiv. 2020 Aug 6:2020.06.23.167544.
2. Hoffmann M, et al. EBioMedicine. 2021 Mar;65:103255.
