Z222979552 | SARS-CoV-2 Mpro inhibitor

Chemical Structure : Z222979552

Z222979552 (Z 222979552)

Catalog No.: PC-73013Not For Human Use, Lab Use Only.

Z222979552 is a small molecule non-covalent SARS-CoV-2 Mpro inhibitor with IC50 of 1.0 uM.

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Biological Activity

Z222979552 is a small molecule non-covalent SARS-CoV-2 Mpro inhibitor with IC50 of 1.0 uM.
Z222979552 inhibits SARS-CoV-2 replication in Vero E6 cells in a dose-dependent manner, prevents the formation of dsRNA intermediates of SARS-CoV-2 RNA synthesis, with no cytotoxic effect.

Physicochemical Properties

M.Wt	392.20
Formula	C16H13IN2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-iodophenyl)-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxamide

References

1. Rossetti GG, et al. Sci Rep. 2022 Feb 15;12(1):2505.

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Z222979552 (Z 222979552)

Biological Activity

Physicochemical Properties

References

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