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Chemical Structure : SB-699551
CAS No.: 791789-61-2
Catalog No.: PC-38716Not For Human Use, Lab Use Only.
SB699551 is a potent, selective 5-HT5A receptor antagonist with pKi of 8.3, >100-fold selectivity over 5-HT1B/D, 5-HT2A, 5-HT2C, 5-HT1A and 5-HT7 receptors.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $298 | In stock | |
| 25 mg | $528 | In stock | |
| 100 mg | Get quote |
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SB699551 is a potent, selective 5-HT5A receptor antagonist with pKi of 8.3, >100-fold selectivity over 5-HT1B/D, 5-HT2A, 5-HT2C, 5-HT1A and 5-HT7 receptors.
SB699551 also is a novel PSMD4/Rpn10 inhibitor, decreases cell viability in MM cell lines.
| M.Wt | 511.754 | |
| Formula | C34H45N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[2-(Dimethylamino)ethyl]-N-[[4'-[[(2-phenylethyl)amino]methyl][1,1'-biphenyl]-4-yl]methyl]cyclopentanepropanamide |
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1. Thomas DR, et al. Neuropharmacology. 2006 Sep;51(3):566-77.
2. Du T, et al. Blood. 2023 Jan 11:blood.2022017897.
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