| Cat. No. |
Product Name |
Information |
| PC-62093 |
YH12852
5-HT4 agonist
|
YH12852 is a potent, highly selective 5-HT4 receptor agonist with pKi of 10.3, exhibits more potent agonistic activity (pEC50=11.4) than both tegaserod and prucalopride. |
| PC-62010 |
VA-012
5-HT2C PAM
|
VA-012 is a potent, selective 5-HT2C receptor positive allosteric modulator (PAM) that exhibits dose-dependent potentiation of 5-HT efficacy with EC50 of 16 nM. |
| PC-61883 |
PF-03382792
5-HT4 agonist
|
PF-03382792 is a potent, brain penetrant 5-HT4 partial agonist with Ki of 2.7 nM and an EC50 of 0.9 nM for 5-HT4d, produces moderate increases in cortical Ach in the rat prefrontal cortex. |
| PC-61868 |
Eletriptan
5-HT1B/1D agonist
|
Eletriptan (UK 116044) is a potent, selective, and orally active 5-HT1B/1D receptor agonist with pKi of 8.0 and 8.9. |
| PC-61867 |
Eletriptan hydrobromide
5-HT1B/1D agonist
|
Eletriptan (UK 116044) hydrobromide is a potent, selective, and orally active 5-HT1B/1D receptor agonist with Ki of 0.92 nM and 3.14 nM respectively. |
| PC-61866 |
GR127935 hydrochloride
5-HT1B/1D antagonist
|
GR-127935 potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor. |
| PC-61865 |
GR127935
5-HT1B/1D antagonist
|
GR127935 is a potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor. |
| PC-61831 |
PF-04995274
5-HT4 agonist
|
PF-04995274 (PF-4995274, TBPT) is a potent, selective, orally active and partial serotonin 4 receptor (5-HT4R) agonist with Ki of 0.15-0.46 nM. |
| PC-61814 |
SB737050A
5-HT6 antagonist
|
SB 737050A is a potent, selective 5-HT6 receptor antagonist to prevent relapse intio addiction. |
| PC-61812 |
GSK-812
|
GSK-812 is a potent neuroprotectant that can induce GDNF in normal and diseased retina, shows has polypharmacology antagonizing multiple receptors, including D2 and D3 receptors, and 5-HT2A, 2C, and 5-HT6 receptors. |
| PC-61729 |
Revexepride
5-HT4 agonist
|
Revexepride (SSP 002358, SPD-557) is a potent, highly selective 5-HT4 receptor agonist for the treatment of gastroesophageal reflux disease. |
| PC-61625 |
Befiradol
5-HT1A agonist
|
Befiradol (F13640, NLX 112) is a highly potent, selective 5-HT1A receptor agonist with Ki of 2.7 nM. |
