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Mosapride citrate

Chemical Structure : Mosapride citrate

CAS No.: 636582-62-2

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Mosapride citrate (AS-4370 citrate;TAK-370)

Catalog No.: PC-62097Not For Human Use, Lab Use Only.

Mosapride citrate (AS-4370 citrate) is a gastroprokinetic agent that acts as a selective 5HT4 agonist.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Mosapride citrate (AS-4370 citrate) is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
Mosapride citrate accelerates gastric emptying throughout the whole of the gastrointestinal tract invivo, and is used for the treatment of gastritis, gastro-oesophageal reflux disease, functional dyspepsia and irritable bowel syndrome.

Physicochemical Properties

M.Wt 614.02
Formula C27H33ClFN3O10
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide citrate

References

1. Kato S, et al. J Med Chem. 1991 Feb;34(2):616-24.

2. Yoshida N, et al. J Pharmacol Exp Ther. 1991 May;257(2):781-7.

3. Sakashita M, et al. Arzneimittelforschung. 1993 Aug;43(8):859-63.

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