| Cat. No. |
Product Name |
Information |
| PC-42254 |
YL0919
5-HT1A antagonist
|
YL0919 (Hypidone hydrochloride) is an orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively. |
| PC-45232 |
Iloperidone
|
Iloperidone (HP-873) is an atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors. |
| PC-45797 |
Setiptiline
α2 adrenoceptor antagonist
|
Setiptiline (Teciptiline, Org8282, MO-8282) is a tetracyclic antidepressant (TeCA) that acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, as well as an H1 receptor inverse agonist/antihistamine. |
| PC-42547 |
WAY-100635
5-HT1A antagonist
|
WAY-100635 (WAY100635) is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor. |
| PC-42653 |
Ketanserin
5-HT2A antagonist
|
Ketanserin (R41468) is a high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C. |
| PC-23392 |
Flucopride
5-HT4R agonist, AChE inhibitor
|
Flucopride is a potent, dual serotonin subtype 4 receptor (5-HT4R) agonist/acetylcholinesterase (AChE) inhibitor with Ki of 9.6 nM (5-HT4R) and IC50 of 24 nM (hAChE). |
| PC-23390 |
Donecopride
5-HT4R agonist, AChE inhibitor
|
Donecopride (MR31147) is a potent, dual serotonin subtype 4 receptor (5-HT4) agonist/acetylcholinesterase (AChE) inhibitor with Ki of 8.5 nM (5-HT4eR) and IC50 of 16 nM (hAChE). |
| PC-23335 |
Ondansetron hydrochloride dihydrate
5-HT3 antagonist
|
Ondansetron hydrochloride dihydrate (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23334 |
Ondansetron hydrochloride
5-HT3 antagonist
|
Ondansetron hydrochloride (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23333 |
Ondansetron
5-HT3 antagonist
|
Ondansetron (GR 38032, SN 307) is a potent, highly selective 5-HT3 receptor antagonist with IC50 of 103 pM. |
| PC-23306 |
Vilazodone
5-HT1A agonist, SSRI
|
Vilazodone (EMD68843, SB659746A) is a potent, dual 5-HT1A agonist and serotonin reuptake inhibitor (SSRI) with IC50 of 0.2 nM at the human 5-HT1A receptor and 0.5 nM for the SERT. |
| PC-23281 |
RS67333 hydrochloride
5-HT4 agonist
|
RS67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum. |
