| Cat. No. |
Product Name |
Information |
| PC-21178 |
25B-NBOMe
5-HT2A agonist
|
25B-NBOMe is a highly selective 5-HT2A receptor agonist with Ki of 0.05 nM, 100-fold selective over 5-HT2C (Ki=4.6 nM). |
| PC-21048 |
NU-1223
5-HT2C agonist
|
NU-1223 is a β carboline analog of alstonine and serotonin 5-HT2C receptor agonist, blocks phencyclidine and amphetamine-induced hyperactivity in subchronic phencyclidine mice. |
| PC-20963 |
Pimavanserin
5-HT2A inverse agonist
|
Pimavanserin (ACP-103) is a potent, selective, orally active 5-HT2A receptor inverse agonist, competitively antagonizes the binding of [(3)H]ketanserin to heterologously expressed human 5-HT(2A) receptors with pKi of 9.3 in membranes and 9.70 in whole cells. |
| PC-20845 |
EMD386088 hydrochloride
5-HT6 agonist
|
EMD386088 hydrochloride is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM. |
| PC-20844 |
EMD386088
5-HT6 agonist
|
EMD386088 is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM. |
| PC-20843 |
SAM-531
5-HT6 agonist
|
SAM-531 (Cerlapirdine, WAY-262531) is a selective, highly potent, 5-HT6 receptor antagonist. |
| PC-49160 |
ASP5736
5-HT5A antagonist
|
AS5736 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 3.6, 1.7 and 4.4 nM against human, rat, mouse 5-HT5A receptors, respectively. |
| PC-49159 |
AS2674723
5-HT5A antagonist
|
AS2674723 is a potent, selective and brain-penetrating 5-HT5A receptor antagonist with Ki of 0.75, 0.67 and 1.9 nM against human, rat, mouse 5-HT5A receptors, respectively. |
| PC-38843 |
Ritanserin
5-HT2 antagonist
|
Ritanserin (R-55667) is a potent, selective and long-acting 5-HT2 receptor antagonist with Ki of 0.39 nM, shows anxiolytic effects. |
| PC-38717 |
UCSF678
5-HT5A agonist
|
UCSF678 is a potent, selective arrestin-biased partial agonist of 5-HT5A serotonin receptor with EC50 of 42 nM. |
| PC-38596 |
SB 224289 hydrochloride
5-HT1B antagonist
|
SB 224289 hydrochloride is a potent, selective 5-HT1B inverse agonist/antagonist with pKi value of 8.16, displays >75-fold selectivity over all other 5-HT receptors. |
| PC-73309 |
Vabicaserin
5-HT2C agonist
|
Vabicaserin (SCA-136) is a potent, selective 5-HT2C receptor full agonist with EC50 of 8 nM, Emax 100%. |
