| Cat. No. |
Product Name |
Information |
| PC-60814 |
MDL100907
5-HT2A inhibitor
|
MDL100907 (Volinanserin) is a potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors. |
| PC-60813 |
25CN-NBOH
5-HT2A agonist
|
25CN-NBOH is a potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM ([3H]ketanserin). |
| PC-60738 |
AZD3676
5-HT1A/1B antagonist
|
AZD3676 is a potent, combined serotonin 5-HT1A and 5-HT1B receptor antagonist with Ki of 0.13 and 2.4 nM in brain homogenates, respectively. |
| PC-60522 |
NBUMP
5-HT1A agonist
|
NBUMP is a potent, highly selective 5-HT1A receptor partial agonist with Ki of 0.1 nM, displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively. |
| PC-60521 |
Minesapride
5-HT4 agonist
|
Minesapride (DSP-6952) is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
| PC-70076 |
Lumateperone
|
Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM). |
| PC-70074 |
Frovatriptan succinate hydrate
5-HT1B/1D agonist
|
Frovatriptan (SB209509, VML251) succinate hydrate is a potent, long lasting 5-HT(1B/1D) receptor agonist with pK50 of 8.2(5-HT1B). |
| PC-60046 |
Landipirdine
5-HT6 antagonist
|
Landipirdine (RO 5025181, SYN-120) is a potent, selective 5-HT6 receptor antagonist, also inhibits 5-HT2A receptor, shows potential for Parkinson's disease (PD). |
| PC-45732 |
NAN-190 hydrobromide
5-HT1A antagonist
|
NAN-190 hydrobromide is a potent, selective 5-HT1A receptor antagonist with Ki of 0.6 nM. |
| PC-42254 |
YL0919
5-HT1A antagonist
|
YL0919 (Hypidone hydrochloride) is an orally active, dual 5-HT1A agonist and selective serotonin reuptake inhibitor with Ki of 0.19 nM and IC50 of 1.78 nM, respectively. |
| PC-45232 |
Iloperidone
|
Iloperidone (HP-873) is an atypical antipsychotic that exhibits high affinity to serotonin 5HT2A (Ki =5.6 nM), dopamine D2 (Ki=6.3 nM) and D3 (Ki=7.1 nM) and noradrenaline α1 receptors (Ki=0.36 nM), moderate affinity for D4 (25 nM), 5HT6 (43 nM), 5HT7 (22 nM), and low affinity for 5HT1A (168 nM), D1 and histamine H1 receptors. |
| PC-42790 |
Risperidone
|
Risperidone (Apexidone, R-64766) is an antipsychotic agent with serotonin-S2 and dopamine-D2 antagonistic properties, also has actions at several 5-HT receptor subtypes, adrenergic receptors and histamine H1 receptors. |
