| Cat. No. |
Product Name |
Information |
| PC-25482 |
Zolmitriptan
5-HT1B/1D receptor agonist
|
Zolmitriptan (BW-311C90, 311C90) is a 5-HT1B/1D receptor partial agonist with Ki values of 5.01 nM, 0.63 nM, and 63.09 nM for 5-HT1B, 5-HT1D, 5-HT1F receptor, respectively. |
| PC-25204 |
Mirtazapine
5-HT antagonist
|
Mirtazapine (Org3770) is a potent and orally active 5-HT2, 5-HT3, histamine H1 receptor and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3 and 6.95, respectively, noradrenergic and specific serotonergic antidepressant (NaSSA) agent. |
| PC-25075 |
(S)-Hydroxy Iloperidone
CAS 501373-88-2
|
(S)-Hydroxy Iloperidone (Milsaperidone) is a metabolite of Iloperidone, which is an atypical antipsychotic, binds to adrenergic α1 and α2c receptors with pKi of 9.2 and 7.7 respectively. |
| PC-25028 |
Remlifanserin
5-HT2A inverse agonist
|
Remlifanserin is a potent, selective 5-HT2A serotonin receptor inverse agonist. |
| PC-25012 |
WAY-208466
5-HT6 agonist
|
WAY-208466 (WAY 208466 dihydrochloride) is a potent and selective 5-HT6 receptor agonist with EC50 of 7.3 nM for human 5-HT6 receptor, shows antidepressant-like and anxiolytic-like effects. |
| PC-24958 |
AVN-101 hydrochloride
5-HT7 antagonist
|
Maritupirdine hydrochloride (AVN-101) is a higly potent, orally bioavailable, BBB permeable 5-HT7 receptor antagonist with Ki of 153 pM, with slightly lesser potency toward 5-HT6, 5-HT2A and 5HT-2C (Ki = 1.2-2.0 nM). |
| PC-24893 |
MDL11939
5-HT2A antagonist
|
MDL11939 (Glemanserin) is a potent and selective antagonist for serotonin receptor 5-HT2A with Ki values of 2.89, 0.54 and 2.5 nM for rat, rabbit and human 5-HT2A receptors, respectively. |
| PC-24892 |
LY272015
5-HT2B antagonist
|
LY272015 hydrochloride is a potent, selective and orally bioactive 5-HT2B receptor (5-HT2BR) antagonist with IC50 of 0.26 nM. |
| PC-24891 |
MARY1
5-HT2B antagonist
|
MARY1 is potent, and selective 5-hydroxytryptamine 2B receptor (5-HT2BR) antagonist with Ki of 764 nM, induces mitochondrial biogenesis (MB) enhances mitochondrial function in the kidney. |
| PC-24876 |
Palonosetron hydrochloride
5-HT3 antagonist
|
Palonosetron (RS 25259-197) is a potent, selective 5-HT3 receptor antagonist with pKi value of 10.4, >10,000-fold selective over 5-HT1A/1D/2A/2C receptors. |
| PC-24462 |
NLX-266
5-HT1A agonist
|
NLX-266 is a potent, selective, orally available and metabolically stable ERK1/2-biased 5-HT1A receptor agonist with binding pKi of 10.35, >1000-fold selective over adrenergic α1 and dopaminergic D2 receptors. |
| PC-24453 |
Brexpiprazole
CAS 913611-97-9
|
Brexpiprazole (OPC-34712) is an atypical orally active antipsychotic agent and partial agonist of human 5-HT1A and dopamine D2L receptor with Ki of 0.12 nM and 0.3 nM, respectively. |
