| Cat. No. |
Product Name |
Information |
| PC-21668 |
PZ-1444
5-HT6R inverse agonist
|
PZ-1444 is a potent, selective partial inverse agonist of 5-HT6 receptor with Ki of 6 nM, IC50 (Gs) of 17.6 nM. |
| PC-21667 |
PZ-1922
5-HT6 antagonist
|
PZ-1922 is a potent, triple-acting 5-HT6R/5-HT3R antagonist and MAO-B reversible inhibitor with Ki of 17/0.45 nM (5-HT6R/5-HT3R), and pIC50 of 8.93 for MAO-B. |
| PC-21666 |
5-HT6 receptor antagonist 15
5-HT6 antagonist
|
5-HT6 receptor antagonist 15 is a first-in-class, selenium containing, highly potent and selective 5-HT6R antagonist with Ki of 14 nM. |
| PC-21178 |
25B-NBOMe
5-HT2A agonist
|
25B-NBOMe is a highly selective 5-HT2A receptor agonist with Ki of 0.05 nM, 100-fold selective over 5-HT2C (Ki=4.6 nM). |
| PC-21048 |
NU-1223
5-HT2C agonist
|
NU-1223 is a β carboline analog of alstonine and serotonin 5-HT2C receptor agonist, blocks phencyclidine and amphetamine-induced hyperactivity in subchronic phencyclidine mice. |
| PC-20845 |
EMD386088 hydrochloride
5-HT6 agonist
|
EMD386088 hydrochloride is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM. |
| PC-20844 |
EMD386088
5-HT6 agonist
|
EMD386088 is a potent, selective 5-HT6 receptor agonist with EC50 of 1.0 nM. |
| PC-20843 |
SAM-531
5-HT6 agonist
|
SAM-531 (Cerlapirdine, WAY-262531) is a selective, highly potent, 5-HT6 receptor antagonist. |
| PC-38596 |
SB 224289 hydrochloride
5-HT1B antagonist
|
SB 224289 hydrochloride is a potent, selective 5-HT1B inverse agonist/antagonist with pKi value of 8.16, displays >75-fold selectivity over all other 5-HT receptors. |
| PC-73302 |
AVN-492
5-HT6 antagonist
|
AVN-492 is a highly potent and selective 5-HT6 receptor antagonist with Ki of 91 pM, >1000-fold selectivity over 5-HT2BR (Ki=170 nM). |
| PC-73301 |
ST1936 oxalate
5-HT6 agonist
|
ST1936 is a potent, selective 5-HT6 receptor agonist with Ki of 13 nM, >10-fold selectivity over 5-HT7 and 5-HT2B receptors. |
| PC-73300 |
LP-211
5-HT7 agonist
|
LP-211 is a potent, selective, and BBB-penetrant 5-HT7 receptor agonist with Ki of 0.58 nM, high selectivity over 5-HT1A receptor (Ki, 188 nM) and D2 receptor (Ki, 142 nM). |
