| Cat. No. |
Product Name |
Information |
| PC-22124 |
CYB210010
5-HT2 receptor agonist
|
CYB210010 is a potent and long-acting serotonin 5-HT2 receptor agonist with Ki values of 0.35 nM and 0.55 nM for 5-HT2A and 5-HT2C receptors respectively. |
| PC-22026 |
GW117
5-HT2C antagonist, MT1/MT2 agonist
|
GW117 is a novel serotonin (5-HT2C) receptor antagonist and melatonin (MT1 /MT2 ) receptor agonist with Ki values of 0.32, 0.12, and 54 nM, respectively. |
| PC-21971 |
Bexicaserin
5-HT2C agonist
|
Bexicaserin (LP532) is a potent, highly selective, oral and centrally acting 5-HT2C receptor agonist, with no detected activity at the 5-HT2B and 5-HT2A receptor subtypes. |
| PC-21829 |
VU6047534
5-HT2B agonist
|
VU6047534 is a selective, peripherally restricted 5-HT2B partial agonist with IC50 of 480 nM in radioligand binding assays. |
| PC-21787 |
5-HT2A antagonist 11c
5-HT2A inhibitor
|
5-HT2A antagonist 11c is a potent, selective, peripheral 5HT2A antagonist with IC50 of 14 nM. |
| PC-21760 |
NH300094
5-HT2A inhibitor
|
NH300094 is a potent antagonist of 5-HT receptors and dopamine receptors with IC50 of 0.47 nM, 1.04 nM, 11.71 nM and 31.55 nM for 5-HT2A, D2L, D2S and D3 receptors, respectively. |
| PC-21671 |
Intepirdine
5-HT6 antagonist
|
Intepirdine (SB742457, GSK-742457) is a potent, highly selective 5-HT6 receptor antagonist with pKi of 9.63. |
| PC-21670 |
Idalopirdine hydrochloride
5-HT6 antagonist
|
Idalopirdine (Lu AE58054) is a potent, selective 5-HT6 receptor antagonist with Ki of 0.83 nM. |
| PC-21669 |
E-6801
5-HT6R agonist
|
E-6801 is a potent, selective 5-HT6 receptor partial agonist of 5-HT6 receptor with pKi of 8.46, cAMP formation EC50 of 8.02. |
| PC-21668 |
PZ-1444
5-HT6R inverse agonist
|
PZ-1444 is a potent, selective partial inverse agonist of 5-HT6 receptor with Ki of 6 nM, IC50 (Gs) of 17.6 nM. |
| PC-21667 |
PZ-1922
5-HT6 antagonist
|
PZ-1922 is a potent, triple-acting 5-HT6R/5-HT3R antagonist and MAO-B reversible inhibitor with Ki of 17/0.45 nM (5-HT6R/5-HT3R), and pIC50 of 8.93 for MAO-B. |
| PC-21666 |
5-HT6 receptor antagonist 15
5-HT6 antagonist
|
5-HT6 receptor antagonist 15 is a first-in-class, selenium containing, highly potent and selective 5-HT6R antagonist with Ki of 14 nM. |
