Catalog No.: PC-61221Not For Human Use, Lab Use Only.
MKC-733 (Pumosetrag, DDP 733) is a potent, selective, orally active 5-HT3 receptor agonist with high affinity for canine intestinal smooth muscle 5-HT3 receptors.
MKC-733 (Pumosetrag, DDP 733) is a potent, selective, orally active 5-HT3 receptor agonist with high affinity for canine intestinal smooth muscle 5-HT3 receptors.
MKC-733 dose dependently stimulates contraction and basal electrolyte secretion in the isolated guinea pig colon, effects that are antagonized by the selective 5-HT3 antagonist ondansetron,.
MKC-733 also accelerates gastric emptying in some animal models.
