| Cat. No. |
Product Name |
Information |
| PC-22491 |
XOB
5-HT2A/VGSC antagonist
|
XOB is a selective antagonist of 5-HT2A receptor and voltage-gated sodium channels, simultaneously antagonizes 5-HT2A receptors and blocks sodium voltage-gated sodium channels (VGSCs). |
| PC-22332 |
ITI-333
5-HT2A agonist
|
ITI-333 is a potent, brain-penetrant, orally bioavailable 5-HT2A receptor antagonist (Ki =8 nM) and a biased, partial agonist at μ-opioid (MOP) receptors (Ki =11 nM, lacking β-arrestin agonism). |
| PC-22310 |
S32212
5-HT2C antagonist
|
S32212 is a combined serotonin (5-HT)(2C) receptor inverse agonist and α(2)-adrenoceptor antagonist with pKi of8.2 (h5-HT2C), pKi of 7.2-8.2 for α(2A), α(2B) and α(2C). |
| PC-22278 |
SB 269970 hydrochloride
5-HT7 antagonist
|
SB269970 (SB-269970) hydrochloride is a potent, selective 5-HT7 receptor antagonist with pKi of 8.9, >100-fold selective over other 5-HT receptors. |
| PC-22276 |
DR4004
5-HT7 antagonist
|
DR4004 (DR-4004) is a potent, highly selective 5-HT7 antagonist with bingding pKi of 8.67, >50-fold selectivity over the 5-HT2 receptor, and other 5-HT receptors. |
| PC-22275 |
DR4004 hydrochloride
5-HT7 antagonist
|
DR4004 (DR-4004) hydrochloride is a potent, highly selective 5-HT7 antagonist with bingding pKi of 8.67, >50-fold selectivity over the 5-HT2 receptor, and other 5-HT receptors. |
| PC-22124 |
CYB210010
5-HT2 receptor agonist
|
CYB210010 is a potent and long-acting serotonin 5-HT2 receptor agonist with Ki values of 0.35 nM and 0.55 nM for 5-HT2A and 5-HT2C receptors respectively. |
| PC-22026 |
GW117
5-HT2C antagonist, MT1/MT2 agonist
|
GW117 is a novel serotonin (5-HT2C) receptor antagonist and melatonin (MT1 /MT2 ) receptor agonist with Ki values of 0.32, 0.12, and 54 nM, respectively. |
| PC-21787 |
5-HT2A antagonist 11c
5-HT2A inhibitor
|
5-HT2A antagonist 11c is a potent, selective, peripheral 5HT2A antagonist with IC50 of 14 nM. |
| PC-21760 |
NH300094
5-HT2A inhibitor
|
NH300094 is a potent antagonist of 5-HT receptors and dopamine receptors with IC50 of 0.47 nM, 1.04 nM, 11.71 nM and 31.55 nM for 5-HT2A, D2L, D2S and D3 receptors, respectively. |
| PC-21671 |
Intepirdine
5-HT6 antagonist
|
Intepirdine (SB742457, GSK-742457) is a potent, highly selective 5-HT6 receptor antagonist with pKi of 9.63. |
| PC-21670 |
Idalopirdine hydrochloride
5-HT6 antagonist
|
Idalopirdine (Lu AE58054) is a potent, selective 5-HT6 receptor antagonist with Ki of 0.83 nM. |
