You are here:Home-Chemical Inhibitors & Agonists-GPCR-5-HT Receptor-SB 269970 hydrochloride
SB 269970 hydrochloride

Chemical Structure : SB 269970 hydrochloride

CAS No.: 261901-57-9

SB 269970 hydrochloride (SB-269970 hydrochloride)

Catalog No.: PC-22278Not For Human Use, Lab Use Only.

SB269970 (SB-269970) hydrochloride is a potent, selective 5-HT7 receptor antagonist with pKi of 8.9, >100-fold selective over other 5-HT receptors.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SB269970 (SB-269970) hydrochloride is a potent, selective 5-HT7 receptor antagonist with pKi of 8.9, >100-fold selective over other 5-HT receptors.
SB-269970 (0.03-1 microM) inhibited the 5-CT concentration-response with no significant alteration in the maximal response.

Physicochemical Properties

M.Wt 388.95
Formula C18H29ClN2O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol hydrochlorid

References

1. Roberts C, et al. Br J Pharmacol. 2001 Apr;132(7):1574-80.

2. Hagan JJ, et al. Br J Pharmacol. 2000 Jun;130(3):539-48.

3. Lovell PJ, et al. J Med Chem. 2000 Feb 10;43(3):342-5.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: