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PZ-1444

Chemical Structure : PZ-1444

CAS No.: 2090144-25-3

PZ-1444 (PZ1444)

Catalog No.: PC-21668Not For Human Use, Lab Use Only.

PZ-1444 is a potent, selective partial inverse agonist of 5-HT6 receptor with Ki of 6 nM, IC50 (Gs) of 17.6 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PZ-1444 is a potent, selective partial inverse agonist of 5-HT6 receptor with Ki of 6 nM, IC50 (Gs) of 17.6 nM.

Physicochemical Properties

M.Wt 339.42
Formula C19H22FN5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2-ethyl-3-(3-fluorobenzyl)-7-(piperazin-1-yl)-3H-imidazo[4,5-b]pyridine)

References

1. David Vanda, et al. J Med Chem. 2021 Jan 28;64(2):1180-1196.

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