PZ-1444 | 5-HT6R inverse agonist | Probechem Biochemicals

Chemical Structure : PZ-1444

Catalog No.: PC-21668Not For Human Use, Lab Use Only.

PZ-1444 is a potent, selective partial inverse agonist of 5-HT6 receptor with Ki of 6 nM, IC50 (Gs) of 17.6 nM.

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Biological Activity

PZ-1444 is a potent, selective partial inverse agonist of 5-HT6 receptor with Ki of 6 nM, IC50 (Gs) of 17.6 nM.

M.Wt	339.42
Formula	C19H22FN5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-ethyl-3-(3-fluorobenzyl)-7-(piperazin-1-yl)-3H-imidazo[4,5-b]pyridine)

1. David Vanda, et al. J Med Chem. 2021 Jan 28;64(2):1180-1196.