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Chemical Structure : VU6047534
Catalog No.: PC-21829Not For Human Use, Lab Use Only.
VU6047534 is a selective, peripherally restricted 5-HT2B partial agonist with IC50 of 480 nM in radioligand binding assays.
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VU6047534 is a selective, peripherally restricted 5-HT2B partial agonist with IC50 of 480 nM in radioligand binding assays.
VU6047534 shows high subtype selectivity relative to 5-HT2A and 5-HT2C (no significant inhibition up to 10 uM).
VU6047534 is peripherally restricted and able to both prevent and treat Sugen-hypoxia-induced pulmonary arterial hypertension.
| M.Wt | 351.42 | |
| Formula | C19H17N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Valentine MS, et al.JACC Basic Transl Sci. 2023 Sep 13;8(10):1379-1388.
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